ArticleEJHaem2026
MRI Predictors of Outcome in Primary Central Nervous System Lymphoma Patients Before and After Autologous Stem Cell Transplant.
Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Introduction: Primary CNS lymphoma (PCNSL) is treated with intensive chemotherapy and autologous stem cell transplant (HDT-ASCT), yet up to one-third of patients relapse. Standard MRI response criteria may not reliably distinguish residual tumour from post-treatment change; additional MRI sequences, such as apparent diffusion coefficient (ADC), could assist in the determination of early relapses, although their prognostic value remains uncertain. Methods: We retrospectively analysed 63 PCNSL patients, assessed pre-HDT-ASCT IPCG response and ADC values, and examined associations with 2-year relapse-free survival. Results: Only pre-HDT-ASCT IPCG status, not the lesion ADC value, significantly predicted the 2-year outcome ( Conclusions: Pre-HDT-ASCT IPCG status, not ADC values, predicts 2-year IPCG status in PCNSL patients.
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