Evidence map›Paper›PMID 42394729›Full record

ArticleFrontiers in oral health2026

Antibacterial performance of biomimetic hydroxyapatite-functionalized titanium surfaces against

Adel S Alagl, Marwa Madi

Abstract read
In one paragraph

Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adel S AlaglDepartment of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Marwa MadiDepartment of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peri-implantitis, driven by bacterial biofilm formation on implant surfaces, remains a leading cause of dental implant failure. Surface modification strategies that combine antibacterial properties with biocompatibility are therefore of considerable clinical interest. This Methods: Commercially available grade 2 titanium discs were divided into HA-coated (Ti-HA) and uncoated (Ti) groups ( Results: Ti-HA surfaces demonstrated substantial antibacterial efficacy across all conditions, with CFU reductions ranging from 97.9% to 99.7% against both Conclusions: These findings provide proof-of-concept evidence that sputtered HA-coated titanium surfaces offer potent antibacterial activity against single and polymicrobial biofilms. While supporting the potential of this dual-function strategy to combine antibacterial protection with osteoconductivity, clinical translation requires further validation under simulated oral conditions that includes salivary pellicle formation and physiological loading as well as comprehensive

Indexed as

Escherichia colifunctionalizedhydroxyapatiteStaphylococcus aureustitanium

Identifiers

PMID42394729
PMCPMC13325720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.