Observational studyEuropean journal of physical and rehabilitation medicine2026
Does apical vertebra location influence the final outcome of bracing for idiopathic scoliosis?
Observational study in European journal of physical and rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIdiopathic scoliosis represents a complex spinal alteration characterized by lateral curvature and rotation of the spine. Among the numerous factors influencing treatment response, the role of the apical vertebra in idiopathic scoliosis remains a topic of significant interest and debate. The apical vertebra, situated at the apex of the scoliotic curve, holds a pivotal position in determining the overall spinal alignment and, consequently, the efficacy of conservative treatments. Several studies have shown that patients with apical vertebrae located in the thoracic spine are more likely to have progression of their curves than patients with apical vertebrae located in the lumbar spine. Additionally, patients with apical vertebrae located in the upper thoracic spine are more likely to have poorer outcomes than patients with apical vertebrae located in the lower thoracic spine. Therefore, understanding the nuanced relationship between the characteristics of the apical vertebra and treatment outcomes is paramount for tailoring therapeutic strategies and optimizing patient care.
aimThis study aims to comprehensively analyze the influence of apical vertebra location and rotation on the outcome of conservative treatment of idiopathic scoliosis.
designThis is an observational controlled cohort study nested in a prospective clinical ongoing database in patients with idiopathic scoliosis.
settingInpatient and outpatient in Rome.
methodsFrom a consecutive series of patients included in a prospective database, we selected 491 patients with Adolescent Idiopathic Scoliosis with curves of 20-40° (mean: 27.89°±5.15°), Risser grade 0-2 who were treated with a brace at 2 years minimum follow-up (mean: 53.62±49.63 months). X-rays were used to obtain Cobb degrees and torsion of the apical vertebrae (Perdriolle's method). Three outcomes were distinguished according to SRS-SOSORT criteria: correction, stabilization, and progression. The location and rotation of the apex vertebra and8 the degrees of the curve were analyzed using statistical analysis.
resultsThe results of our study showed that, among 491 patients with a definite outcome, the Cobb mean value was 27.89±5.158 SD at baseline and 16.99±15.85 SD at follow-up (P<0.0001; R=0.3228). Perdriolle was initially 11.9±7.319 and 7.319±7.816 at follow-up (P<0.0001, R=0.4865). Overall, 411 patients (84%) achieved curve correction, and stabilization was attained in 70 cases (14%). Ten patients (2%) experienced curve progression, and one patient was recommended for surgery because the curve at follow-up was greater than 45°. The analysis of subgroups shows statistically significant differences in the means of L1 and D9, L1 and D8, L1 and D7, L2 and D7, and D12 and D7; the P values are less than 0.05 (Table I). Moreover, a significant correlation was observed between the apex vertebra and the mean Cobb correction (P<0.0001) (R=0.64).
conclusionsOur study demonstrates that the apical vertebra plays a significant role in the outcome of conservative treatment for AIS. Patients with apical vertebrae located in the thoracic spine, particularly in the upper thoracic spine, were more likely to have poorer outcomes compared to patients with apical vertebrae located in the lumbar spine. CLINICAL REHABILITATION IMPACT: These findings highlight the importance of considering the location of the apical vertebra when determining the prognosis and treatment plan for patients with AIS. Moreover, we can affirm that brace treatment is an effective method for the treatment of AIS, in fact, the majority of patients achieved curve correction and stabilization, with a low incidence of curve progression and surgery.
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