Evidence map›Paper›PMID 42394179›Full record

ArticleNeuropsychopharmacology reports2026

Comment on "Serum Amyloid β Oligomer May Predict Treatment Response in Middle-Aged and Late-Life Patients With Depression".

Stjepan Škudar

Abstract readCommentLetter
In one paragraph

Article in Neuropsychopharmacology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Stjepan ŠkudarFamily Medicine, Zagreb West Health Center, Zagreb, Croatia.ORCID https://orcid.org/0009-0006-8852-2875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum Aβ oligomer positivity may indicate neurodegenerative vulnerability and may be associated with poorer antidepressant treatment response in middle-aged and late-life depression. Further validation using amyloid PET, tau biomarkers, standardized treatment protocols, and longitudinal cognitive follow-up is needed.

Indexed as

Amyloid beta-PeptidesAntidepressive AgentsDepressionBiomarkersHumansTreatment OutcomeAmyloid beta-PeptidesAntidepressive AgentsBiomarkers

Identifiers

PMID42394179
PMCPMC13328844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.