Evidence map›Paper›PMID 42394120›Full record

ArticleExperimental physiology2026

Galectin-3 plasma levels are associated with left atrial contractile function in long-distance runners.

Felipe Contreras-Briceño, Fernanda Sanhueza-Olivares, Rodrigo Fernández, Silvana Llevaneras, Pablo F Castro, Luigi Gabrielli, Mario Chiong

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Felipe Contreras-BriceñoInstituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile.ORCID https://orcid.org/0000-0002-0674-7506
Fernanda Sanhueza-OlivaresAdvanced Center for Chronic Diseases, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0009-0001-8592-7598
Rodrigo FernándezUnidad de Investigación Científica, Hospital Base San José, Osorno, Chile.
Silvana LlevanerasAdvanced Center for Chronic Diseases, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pablo F CastroAdvanced Center for Chronic Diseases, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-9320-1703
Luigi GabrielliAdvanced Center for Chronic Diseases, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-1551-7147
Mario ChiongAdvanced Center for Chronic Diseases, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-5174-6545

Funding

FONDAP ACCDiS 15130011FONDAP ACCDiS 1523A00008Fondo Nacional de Desarrollo Científico y Tecnológico 1170963Fondo Nacional de Desarrollo Científico y Tecnológico 1180157Fondo Nacional de Desarrollo Científico y Tecnológico 1220293Plataforma ICAI de la Universidad de Chile FIU-138310Publication Support Fund
6 · The paper itself

Abstract

High-intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis-related biomarkers and whether these biomarkers track with atrial function in a training volume-dependent manner remains unclear. This study, with within-subject pre- and post-marathon comparisons, evaluated plasma galectin-3 and amino-terminal type III procollagen propeptide (PIIINP) in 36 male long-distance runners before and immediately after completion of a marathon and examined their relationship to atrial function assessed by speckle-tracking echocardiography. Participants were stratified into high-training (HT; ≥100 km week

Indexed as

atrial strainbiomarkerechocardiographyexerciseheartmyocardial fibrosisrunning

Identifiers

PMID42394120
PMCPMC13394894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.