Evidence map›Paper›PMID 42393705›Full record

SynthesisBMC veterinary research2026

Pseudorabies virus in wild swine: current evidence and interpretations from monitoring studies.

Thomas Müller, Nicolai Denzin, Conrad M Freuling

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas MüllerInstitute for Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, Greifswald-Insel Riems, 17493, Germany. thomas.mueller@fli.de.ORCID https://orcid.org/0000-0002-0959-3653
Nicolai DenzinInstitute for Epidemiology, Friedrich-Loeffler-Institut, Südufer 10, Greifswald-Insel Riems, Germany, Germany.
Conrad M FreulingInstitute for Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, Greifswald-Insel Riems, 17493, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To synthesize current knowledge on pseudorabies virus (PRV; also known as Aujeszky's disease virus or Suid alphaherpesvirus 1) infections in wild swine, a combined review and meta-analysis was conducted. The study aimed to critically interpret reported PRV seroprevalence data, assess risks for animal health and disease control programs, and inform future monitoring and management strategies. An extensive literature search covering the period from 1970 to 2025 identified 160 serosurveys published between 1979 and 2024, yielding 516 datasets for analysis. Binomial logistic and mixed-effects logistic regression models were used to assess spatio-temporal patterns. The results indicate that PRV is widely established in wild swine populations, particularly in Europe and North America, forming stable endemic cycles largely independent of host density. Persistent spatial heterogeneity and region-specific temporal trends were observed, and once introduced into naïve populations, PRV appears to persist long term, limiting the added value of continued monitoring in long-established endemic areas.

Indexed as

Herpesvirus 1, SuidPseudorabiesSwine DiseasesAnimalsAnimals, WildEuropeNorth AmericaSeroepidemiologic StudiesSwineAujeszky's diseaseGlobal situationMonitoringPseudorabies virusSuid alphaherpesvirus 1Wild swine

Identifiers

PMID42393705
PMCPMC13334763

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.