Evidence map›Paper›PMID 42393653›Full record

ArticleBMC women's health2026

Comparison of four imaging modalities for cesarean scar defect: a retrospective study.

Xingchen Zhou, Mingjuan Zhou, Huayuan Qiao, Xipeng Wang

Abstract readComparative Study
In one paragraph

Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xingchen Zhou *Department of Gynecology and obstetrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kong Jiang Rd, Yang Pu District, Shanghai, 200092, China.
Mingjuan Zhou *Department of Gynecology and obstetrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kong Jiang Rd, Yang Pu District, Shanghai, 200092, China.
Huayuan QiaoDepartment of Gynecology and obstetrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kong Jiang Rd, Yang Pu District, Shanghai, 200092, China.
Xipeng WangDepartment of Gynecology and obstetrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kong Jiang Rd, Yang Pu District, Shanghai, 200092, China. wangxipeng@xinhuamed.com.cn.

Funding

National Natural Science Foundation of China 82501956National Natural Science Foundation of China 82501989
6 · The paper itself

Abstract

BACKGROUND AND

aimsWe compared four imaging methods: transvaginal ultrasound(TVU), magnetic resonance imaging(MRI), saline contrast-enhanced MRI (SCE_MRI) and hysteroscopy combined with transabdominal ultrasound (HSC_TAU) for evaluating cesarean scar defect(CSD) morphology and clinical correlations.

methodsSixty-one women with prior cesarean delivery and prolonged menstrual bleeding underwent all four imaging modalities within days 7-14 of a single menstrual cycle. We measured CSD length, width, depth, and residual myometrial thickness (TRM), and compared detection rates and severity classification, and the linear regression between CSD length and menstrual bleeding duration.

resultsHSC_TAU detected CSD in 100% of patients, compared to 94% for TVU, 97% for MRI, and 97% for SCE_MRI. HSC_TAU measured longer CSD length (median 15.4 mm) than TVU (6.5 mm), MRI (8.0 mm), and SCE_MRI (8.2 mm) (P < 0.001). TVU measured thicker TRM (median 2.7 mm) than HSC_TAU (2.0 mm), MRI (2.0 mm), and SCE_MRI (1.8 mm) (P < 0.001). Using TRM < 2.5 mm as the threshold for severe CSD, TVU identified only 43% of cases as severe, while HSC_TAU, MRI, and SCE_MRI identified 66-77%. The linear regression analysis revealed a significant association between HSC_TAU-measured CSD length and menstrual bleeding duration (regression coefficient β = 0.24, 95% CI: 0.08-0.30, R² = 0.14, p = 0.003).

conclusionHSC_TAU offers high detection rate and reliable TRM measurement. TVU tends to underestimate CSD size and overestimate TRM, which may lead to underdiagnosis of severe cases. We suggest using TVU for initial screening and HSC_TAU for preoperative evaluation in symptomatic patients.

Indexed as

Cesarean SectionCicatrixMagnetic Resonance ImagingAdultFemaleHumansHysteroscopyRetrospective StudiesUltrasonographyAbnormal uterine bleedingCesarean scar defectHysteroscopyIsthmoceleUltrasound

Identifiers

PMID42393653
PMCPMC13595662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.