ArticleBMC microbiology2026
Insights into antimicrobial resistance: dissemination and molecular epidemiology of carbapenemase and AmpC genes in uropathogenic Escherichia coli.
Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study investigated the prevalence of acquired/natural AmpC β-lactamase genes (ABLGs) and acquired carbapenemase genes (ACGs) and their association with antimicrobial resistance in uropathogenic Escherichia coli (UPEC).
methodsA total of 105 non-duplicate UPEC isolates recovered from urine specimens collected in Tehran, Iran (August 2023-January 2024), were analyzed. Antimicrobial susceptibility testing was performed by the Kirby-Bauer method. ESBL and AmpC phenotypes were determined phenotypically, and bla
resultsResistance to ampicillin and amoxicillin was observed in all isolates, followed by ciprofloxacin (75.24%), ofloxacin (60.95%), and cefotaxime (60.95%). ESBL and AmpC phenotypes were detected in 37.14% and 11.43% of isolates, respectively. MDR, XDR, and PDR phenotypes occurred in 55.24%, 16.19%, and 2.86% of isolates. The most prevalent β-lactamase genes (BLGs) were bla
conclusionsUPEC isolates from Tehran exhibited substantial antimicrobial resistance, including MDR, XDR, and PDR phenotypes. ESBL and AmpC producers were common, with bla
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