Evidence map›Paper›PMID 42393451›Full record

ReviewAdvances and technical standards in neurosurgery2026

Anterior Odontoid Screw Fixation: Current Advances in Indications and Techniques.

Gianpaolo Jannelli, Benedetta Fazzolari, Andrea Brunori, Aria Nouri, Enrico Tessitore, Alberto Delitala

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In one paragraph

Review in Advances and technical standards in neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gianpaolo JannelliDepartment of Neurosurgery, Geneva University Hospitals and University of Geneva Faculty of Medicine, Geneva, Switzerland.
Benedetta FazzolariNeurosurgical Unit, San Camillo Forlanini Hospital, Rome, Italy. bfazzolari@scamilloforlanini.rm.it.
Andrea BrunoriNeurosurgical Unit, San Camillo Forlanini Hospital, Rome, Italy.
Aria NouriDepartment of Neurosurgery, Geneva University Hospitals and University of Geneva Faculty of Medicine, Geneva, Switzerland.
Enrico TessitoreDepartment of Neurosurgery, Geneva University Hospitals and University of Geneva Faculty of Medicine, Geneva, Switzerland.
Alberto DelitalaSan Carlo di Nancy Hospital, GVM Care & Research, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOdontoid fractures (OFs) are one of the most common fractures of the upper cervical spine, estimated to represent 9-15% of all cervical fractures. Although their relative frequency, its optimal management is still debated. When surgery is required, anterior odontoid screw fixation (AOSF) offers several advantages, such as preservation of neck rotation, reduced surgical risk, and shorter hospital stay. However, only well-selected patients are eligible for this procedure, and an accurate interpretation of imaging as well as an optimal surgical timing should be taken into account to identify who may be the "best candidates".

methodsThe aim of this narrative review is to report the current advances in the treatment of OFs by AOSF. We will focus on surgical details, including minimally invasive surgery, as well as on pre- and postoperative critical aspects.

resultsWith regard to preoperative imaging, type II b OFs (with fracture line oriented from anterior superior to posterior inferior) typically present favourable configuration to be treated by AOSF. Furthermore, a fracture gap >2 mm, an angulation >11° and a displacement >2 mm as well as timing duration from injury to surgery >7 days are predictors of non-union after AOSF. With regard to surgical technique, compared to traditional open technique, MIS procedures are more and more reported. This approach can be performed percutaneously under fluoroscopy or navigation guidance. Finally, the use of a single, bicortical lag screw is strongly suggested to compress the fractured bone surfaces, to reduce the fracture gap and to obtain the best mechanical stability.

conclusionOur review suggests that AOSF is an effective option in the treatment of type II OFs. However, a meticulous assessment of preoperative images is mandatory, and particular attention has to be paid to fracture configuration, gap, angulation, displacement and ligament integrity. With regard to elderly population, the possibility of wearing rigid collar should be considered, and recent literature reports encouraging results even without any treatment. If a surgical intervention is required, the timing from injury to the operation represents a crucial parameter, making early decisions an important element in the management of type II OFs. Compared to the traditional open approach, minimally invasive AOSF is reliable, promotes faster recovery and in select cases can be performed even under sedation.

Indexed as

Bone ScrewsFracture Fixation, InternalOdontoid ProcessSpinal FracturesHumansMinimally Invasive Surgical ProceduresAnterior odontoid screw fixationC2 odontoid process fracturesConservative treatment odontoid fracturesMinimally invasive treatment odontoid fracturesOdontoid fracturesOdontoid process screw fixationPosterior fixation C1-C2

Identifiers

PMID42393451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.