ArticleInternational journal of obesity (2005)2026
Target tissue insulin resistance in early and late onset of overweight or obesity.
Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectiveOverweight and obesity are associated with insulin resistance. However, the importance of the time of onset of excess body fat is unknown and was presently examined. SUBJECTS/
methodsWe included 339 adult participants having information about their body mass index (BMI) at 18 years of age. Insulin action was determined as homeostasis model assessment (HOMA-IR) reflecting liver, hyperinsulinemic euglycemic clamp reflecting skeletal muscle, Adipo-IR reflecting adipose tissue in vivo, and insulin action on lipogeneses reflecting fat cells. The subjects were divided into never having overweight/obesity with BMI always <25 kg/m
resultsEO had 5 kg/m
conclusionWhen current BMI or age is considered, there is no difference between early or late onset of overweight/obesity for the level of insulin resistance in the different target tissues of the hormone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.