Evidence map›Paper›PMID 42393243›Full record

ArticleAnalytical and bioanalytical chemistry2026

Smartphone-integrated one-step colorimetric glucose detection at physiological pH enabled by a haloperoxidase mimic.

Yongfang Zheng, Shuijing Huang, Xinyu Zhu, Yuyuan Chen, Shuli Tian, Yuxuan Pang, Chaojie Zhuang, Hu Zhu

Abstract read
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Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yongfang Zheng *Fujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Shuijing Huang *Fujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Xinyu ZhuFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Yuyuan ChenFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Shuli TianFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Yuxuan PangFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Chaojie ZhuangFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China.
Hu ZhuFujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering, Engineering Research Center of Industrial Biocatalysis, Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, 32 Shangsan Road, Fuzhou, 350007, China. zhuhu@fjnu.edu.cn.

Funding

Fu-Xia-Quan National Independent Innovation Demonstration Zone Collaborative Innovation Platform Project 2022FX3Major Scientific Research Program for Young and Middle-aged Health Professionals of Fujian Province, China 2023ZQNZD020Natural Science Foundation of Fujian Province of China 2023H6011Natural Science Foundation of Fujian Province of China 2025J01631Program for Innovative Research Team in Science and Technology in Fujian Province University, 100 Talents Program of Fujian Province, Fujian-Taiwan Science and Technology Cooperation Base of Biomedical Materials and Tissue Engineering 2021D039the Natural Science Foundation of China 22307018the Natural Science Foundation of China U1805234
6 · The paper itself

Abstract

Nanozymes (primarily peroxidase mimics) coupled with glucose oxidase (GOx) have emerged as an important approach for glucose sensing. However, the widespread application of this strategy is hampered by a critical pH mismatch, as most such nanozymes require an acidic environment for high activity, preventing one-step detection at physiological pH. Here, we report a cascade colorimetric sensing platform based on our previously reported haloperoxidase (HPO) mimic HH-Cu, which exhibits high HPO-like activity exclusively under neutral and alkaline conditions, enabling one-step glucose detection at physiological pH. In this system, GOx catalyzes the oxidation of glucose to generate H

Indexed as

ColorimetryGlucosePeroxidasesBiosensing TechniquesGlucose OxidaseHumansHydrogen-Ion ConcentrationHydrogen PeroxideLimit of DetectionGlucoseGlucose OxidaseHydrogen PeroxidePeroxidasesGlucose detectionHaloperoxidase mimicOne-stepUnder physiological condition

Identifiers

PMID42393243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.