Evidence map›Paper›PMID 42393082›Full record

ReviewNature reviews. Disease primers2026

Accidental hypothermia.

Tomasz Darocha, Mathieu Pasquier, Konrad Mendrala, Michał Pluta, Kazue Oshiro, Justyna Swol, Silvia Mariani, Alice Hutin, Paweł Podsiadło, Sylweriusz Kosiński

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomasz Darocha *Department of Anaesthesiology and Intensive Care, Medical University of Silesia, Katowice, Poland. tdarocha@sum.edu.pl.ORCID http://orcid.org/0000-0001-5889-3209
Mathieu Pasquier *Department of Emergency Medicine, Lausanne University Hospital, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-0042-5909
Konrad MendralaDepartment of Anaesthesiology and Intensive Care, Medical University of Silesia, Katowice, Poland.
Michał PlutaDepartment of Acute Medicine, Medical University of Silesia, Zabrze, Poland.
Kazue OshiroDepartment of Cardiovascular Medicine and Mountain Medicine, Research, and Survey Division, Sapporo Kojinkai Memorial Hospital, Sapporo, Japan.ORCID http://orcid.org/0000-0003-1248-0737
Justyna SwolDepartment of Respiratory Medicine, Paracelsus Medical University Nuremberg, Nuremberg, Germany.
Silvia MarianiCardiac Surgery Unit, Cardiothoracic and Vascular Department, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Alice HutinSAMU de Paris, Necker University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Paweł PodsiadłoDepartment of Emergency Medicine, Jan Kochanowski University, Kielce, Poland.ORCID http://orcid.org/0000-0002-1069-2659
Sylweriusz KosińskiMountain Medicine Laboratory, Jagiellonian University Medical College, Krakow, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accidental hypothermia is an unintentional drop in core body temperature below 35 °C. It can occur at any time of year and in any climate, and can affect all age groups. The epidemiology of accidental hypothermia reflects the interaction between biological susceptibility, social conditions and exposure to environmental factors. As core temperature falls and thermoregulation mechanisms become insufficient, the metabolism slows, consciousness deteriorates and the hypothermic myocardium becomes increasingly prone to arrhythmias and cardiac arrest. The prognosis is variable, and treatment outcomes are dependent on multiple factors, with cardiac arrest being the decisive determinant, carrying an in-hospital mortality rate of up to 50%. Diagnosis relies on accurate core temperature measurement whenever possible, together with clinical staging when measurement is unavailable. The management of accidental hypothermia should follow the hypothermic chain of survival: prevent further cooling, handle the patient gently, provide airway, breathing and circulatory support, choose the correct destination hospital, and rewarm the patient using passive, active external, active internal or extracorporeal techniques according to severity. Extracorporeal life support is crucial for patients with hypothermic cardiac arrest. Most survivors of hypothermic cardiac arrest have excellent neurological outcomes. Effective prevention and education, together with well-organized regional pathways of care and personalized strategies to prevent cardiac arrest, are needed to improve outcomes.

Indexed as

Body Temperature RegulationHeart ArrestHypothermiaRewarmingBody TemperatureCold TemperatureExtracorporeal Membrane OxygenationHospital MortalityHumansPrognosisTreatment Outcome

Identifiers

PMID42393082

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.