Evidence map›Paper›PMID 42392692›Full record

ArticleRadiation oncology journal2026

Boron neutron capture therapy for recurrent pediatric sialoblastoma: the first clinical experience and dosimetric considerations for skeletal safety with 4-year follow-up.

Hung-Ruei Liao, Yi-Yen Lee, Chih-Ying Lee, Syuan-Ting Chang, Ko-Han Lin, Fong-In Chou, Jinn-Jer Peir, Hong-Ming Liu, Yi-Wei Chen

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Article in Radiation oncology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hung-Ruei LiaoDepartment of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
Yi-Yen LeeTaipei Veterans General Hospital Neurosurgical Department, Division of General Neurosurgery, Taipei, Taiwan, R.O.C.
Chih-Ying LeeDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
Syuan-Ting ChangSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.
Ko-Han LinDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.
Fong-In ChouNuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan, R.O.C.
Jinn-Jer PeirNuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan, R.O.C.
Hong-Ming LiuNuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan, R.O.C.
Yi-Wei ChenDepartment of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialoblastoma is a rare, aggressive pediatric salivary gland tumor often refractory to conventional therapies, which carry significant risks of growth impairment in children. We report the 52-month follow-up of a 6-year-old girl with recurrent sialoblastoma treated with two sessions of boron neutron capture therapy (BNCT). She achieved a 23-month complete response after the first session and a sustained partial response following the second. Dosimetric analysis using a conservative α/β ratio of 2.0 Gy for late-responding tissues showed that the equivalent dose in 2-Gy fractions to the mandible area was approximately 4.3 Gy-Eq. This is substantially below the 15 Gy threshold recognized for skeletal impairment. Our findings suggest that BNCT is a highly selective salvage option that effectively controls refractory pediatric tumors while preserving craniofacial development.

Indexed as

Bone developmentBoron neutron capture therapyPediatricsRecurrentSialoblastoma

Identifiers

PMID42392692
PMCPMC13327805

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.