Evidence map›Paper›PMID 42392671›Full record

ArticleBMJ health & care informatics2026

Detection of cancer recurrence from Thai-English electronic medical records using sentence embeddings.

Ekapob Sangariyavanich, Wanchana Ponthongmak, Nawanan Theera-Ampornpunt, Nat Tangchitnob, Gareth J McKay, Ammarin Thakkinstian

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Article in BMJ health & care informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ekapob SangariyavanichNational Cancer Institute of Thailand, Bangkok, Thailand.ORCID http://orcid.org/0000-0002-1009-7382
Wanchana PonthongmakDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand wanchana.pon@mahidol.ac.th.
Nawanan Theera-AmpornpuntDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Nat TangchitnobDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Gareth J McKayCentre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, UK.
Ammarin ThakkinstianDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study developed and validated monolingual and bilingual sentence-bidirectional encoder representations from transformers (SBERT) models for detecting cancer recurrence within Thai-English electronic medical records (EMRs) from Thai cancer hospitals.

methodA multicentre dataset of 32 436 documents from 1250 patients was used for model development. External validation involved an independent dataset of 9244 documents from 384 patients across two Thai cancer hospitals. Performance was benchmarked against a fine-tuned PubMedBERT (MetBERT).

resultsThe development dataset included breast (43.9%), colorectal (12.1%), cervical (28.0%) and head and neck (16.0%) cancers. MetBERT achieved the highest area under the precision-recall curve (AUPRC) for locoregional versus no recurrence (11.1%) and locoregional versus distant recurrence (91.7%), while monolingual-SBERT excelled at distant versus no recurrence (32.0%). External validation demonstrated MetBERT superiority for locoregional versus no recurrence (9.30%-21.50%). For distant versus no recurrence, bilingual-SBERT performed best with AUPRC 17.55%-24.39%. While MetBERT led in distinguishing locoregional versus distant recurrence (88.30%-94.70%), bilingual-SBERT demonstrated robust external validation performance (AUPRC 85.25%-91.80%). DISCUSSION: Low AUPRC values (9%-32%) reflect the extreme class imbalance in real-world data (~1% recurrence prevalence). Despite this, fine-tuned MetBERT achieved highest performance, while bilingual-SBERT demonstrated superior robustness during external validation. This validates sentence embedding models for handling mixed Thai-English medical records in multilingual clinical environments.

conclusionSentence embedding frameworks provide a practical, generalisable solution for detecting cancer recurrence within multilingual EMRs. Despite text-length constraints, these models are suitable for clinical integration as a screening tool for cancer registry workflows.

Indexed as

Electronic Health RecordsNatural Language ProcessingNeoplasm Recurrence, LocalHumansThailandElectronic Health RecordsNatural Language Processing

Identifiers

PMID42392671
PMCPMC13330879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.