SynthesisSurgical endoscopy2026
Minimally invasive versus open surgery for adhesive small bowel obstruction: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdhesive small bowel obstruction (ASBO) is a common surgical emergency. However, open adhesiolysis has traditionally been the standard operative approach after failed conservative management. The aim was comparing postoperative outcomes between laparoscopic and open adhesiolysis in ASBO.
methodsA systematic review and meta-analysis was conducted according to PRISMA 2020 and Cochrane guidelines. PubMed, Embase, Scopus, Web of Science, and BVS were searched from inception to September 2025. Randomized controlled trials (RCTs) and comparative cohort studies evaluating laparoscopic versus open adhesiolysis in adults with ASBO were included. Random-effects models were applied. Risk ratios (RR) and mean differences (MD) with 95% confidence intervals (CI) were calculated. Risk of bias was assessed using ROBINS-I and RoB 2. Certainty of evidence was evaluated with GRADE.
resultsFifteen studies (22,409 patients; 14 retrospective cohorts and 1 RCT) were included. Meta-analysis of observational studies showed that laparoscopic adhesiolysis was associated with lower postoperative mortality (13 studies; RR 0.33, 95% CI 0.24 to 0.45; I
conclusionsIn selected adults with ASBO, laparoscopic adhesiolysis is associated with improved early postoperative outcomes compared with open surgery, although overall certainty of evidence remains limited.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.