Evidence map›Paper›PMID 42390795›Full record

ArticleStress biology2026

BUI1 coordinates actin cytoskeleton remodeling and ROS homeostasis to confer broad-spectrum disease resistance in rice.

Hui Lin, Kaixuan Cui, Jingyi Wang, Yanlong Jin, Xi Zhang, Yiduo Lu, Xuanxuan Wu, Li Zhang, Shasha Liu, Jiyun Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stress biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hui Lin *State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China. hlin@cemps.ac.cn.ORCID http://orcid.org/0000-0003-4003-5972
Kaixuan Cui *Shanghai Agricultural Technology Extension and Service Center, Shanghai, 201103, China.
Jingyi Wang *Ministry of Education Key Laboratory for Biodiversity, Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Yanlong JinMinistry of Education Key Laboratory for Biodiversity, Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Xi ZhangMinistry of Education Key Laboratory for Biodiversity, Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, School of Life Sciences, Fudan University, Shanghai, 200433, China.
Yiduo LuState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Xuanxuan WuCollege of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Li ZhangState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Shasha LiuKey Laboratory of Plant Stress Biology, State Key Laboratory of Cotton Biology, School of Life Sciences, Henan University, Kaifeng, 475004, China.
Jiyun LiuState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Qun LiState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Yiwen DengCollege of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Weibing YangState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Zuhua HeState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
Mingjun GaoMinistry of Education Key Laboratory for Biodiversity, Science and Ecological Engineering, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, School of Life Sciences, Fudan University, Shanghai, 200433, China. mjgao@fudan.edu.cn.

Funding

National Key Research and Development Program of China 2023YFC2604500
6 · The paper itself

Abstract

The cytoskeleton functions as a dynamic intracellular structural scaffold, enabling cells to rapidly respond to biotic and abiotic stresses. During plant innate immunity, the cytoskeleton undergoes significant actin remodeling. Using the rice-Magnaporthe oryzae pathosystem, we demonstrate that pattern-triggered immunity (PTI) induces a rapid and transient actin filament reorganization dependent on the Class II formin protein BENT UPPERMOST INTERNODE1 (BUI1). Disruption of actin filaments using latrunculin B significantly enhances host susceptibility to the blast fungus M. oryzae. Importantly, the bui1 mutant exhibits compromised resistance not only to blast but also to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae and the sheath blight fungus Rhizoctonia solani. We identify that this enhanced susceptibility to multiple pathogens stems from increased ROS scavenging activity in bui1, mediated by upregulation of peroxidase-encoding genes and consequent reduction in H₂O₂ accumulation. Furthermore, genetic analyses reveal that BUI1 acts downstream of the immunity suppressor RESISTANCE OF RICE TO DISEASES1 (ROD1), as the bui1 mutation compromises rod1-mediated broad-spectrum resistance. Our findings establish BUI1 as a key regulator linking cytoskeletal reorganization to receptor-mediated immune signaling and ROS homeostasis during plant-pathogen interactions, providing new insights into the integration of actin dynamics with plant defense mechanisms.

Indexed as

Actin cytoskeletonBUI1rod1ROSSusceptibility

Identifiers

PMID42390795
PMCPMC13328597

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.