Evidence map›Paper›PMID 42390778›Full record

ReviewAbdominal radiology (New York)2026

Seeing the invisible: practical strategies to maximize the clinical impact of photon-counting CT in abdominal imaging.

Kota Yokoyama, Yusuke Kawasaki, Mikiya Fujii, Hirofumi Yamada, Junichi Tsuchiya, Takumi Hiraishi, Hiroto Hada, Kurara Yamamoto, Daisuke Asano, Daisuke Ban and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kota YokoyamaDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan. kota1986ky@yahoo.co.jp.
Yusuke KawasakiDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan.
Mikiya FujiiDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan.
Hirofumi YamadaDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan.
Junichi TsuchiyaDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan.
Takumi HiraishiRadiology Center, Institute of Science Tokyo Hospital, Tokyo, Japan.
Hiroto HadaRadiology Center, Institute of Science Tokyo Hospital, Tokyo, Japan.
Kurara YamamotoDepartment of Pathology, Institute of Science Tokyo, Tokyo, Japan.
Daisuke AsanoDepartment of Hepatobiliary Surgery, Institute of Science Tokyo, Tokyo, Japan.
Daisuke BanDepartment of Hepatobiliary Surgery, Institute of Science Tokyo, Tokyo, Japan.
Marie HanaokaGastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Kimio WakanaDepartment of Obstetrics & Gynecology, Institute of Science Tokyo, Tokyo, Japan.
Masateru TakigawaDepartment of Cardiology, Institute of Science Tokyo, Tokyo, Japan.
Takehiko MoriDepartment of Hematology, Institute of Science Tokyo, Tokyo, Japan.
Ukihide TateishiDepartment of Diagnostic Radiology and Nuclear Medicine, Institute of Science Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photon-counting detector computed tomography (PCD-CT) represents a major technological advance, transforming abdominal imaging from morphology-based assessment to a platform that integrates spectral and quantitative information. Unlike conventional energy-integrating detector CT, PCD-CT directly converts X-ray photons into electrical signals, allowing inherent spectral imaging, improved spatial resolution, and enhanced dose efficiency. These characteristics enable flexible retrospective reconstruction, including virtual monoenergetic imaging and material decomposition, which can be tailored to specific clinical tasks and applications. These capabilities translate into meaningful clinical benefits in abdominal radiology. Low-keV imaging improves lesion conspicuity, facilitating the detection of subtle findings including early-stage pancreatic cancer, small metastases, and inflammatory changes. Further, spectral imaging improves tissue characterization, enabling differentiation between true and pseudoenhancement and supporting more accurate staging in oncologic imaging. Moreover, amplifying iodine contrast may enable substantial contrast dose reduction while maintaining diagnostic quality, potentially benefiting selected patients who require contrast optimization. PCD-CT may support the concept of "one-stop imaging" by providing both systemic and local diagnostic information within a single examination, potentially reducing the need for additional imaging in selected clinical scenarios. Quantitative imaging approaches, including iodine density mapping and extracellular volume assessment, provide functional information that may serve as imaging biomarkers for disease activity and treatment response. Emerging applications, including virtual noncalcium imaging, expand the role of CT into domains traditionally reserved for magnetic resonance imaging. Challenges including increased data volume, technical limitations, cost-effectiveness, and the need for optimized reconstruction strategies, remain despite these advantages. PCD-CT is poised to play a key role in abdominal radiology, shifting CT from simply "seeing more" to "measuring more" and "understanding more" as multi-energy imaging and quantitative techniques continue to evolve.

Indexed as

Dose reductionIodine mappingPhoton-counting CTSpectral imagingUltra-high-resolutionVirtual monoenergetic imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.