Evidence map›Paper›PMID 42390269›Full record

ArticleJournal of virology2026

Dysregulation of miRNAs has broad impacts on virus infection in

Tyson G Thomson, Daniel Chew, Karyn N Johnson

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tyson G Thomson *School of the Environment, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0009-0000-5532-748X
Daniel Chew *School of the Environment, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-3049-5126
Karyn N JohnsonSchool of the Environment, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-8647-8985

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal microRNAs (miRNAs) are important post-transcriptional regulators of gene expression. While the impact of certain miRNAs on viruses is well established, the frequency and magnitude of impacts more broadly are largely unknown. To address this, we screened the functional impact that the dysregulation of 34 individual miRNAs had on virus infection using a panel of three distinct RNA viruses: Drosophila C virus ( IMPORTANCE: A clear understanding of how host and virus interact is fundamental in developing techniques to reduce virus infection. Animal microRNAs (miRNAs) are a group of genetic regulators that have been shown to impact host and virus interactions. However, the frequency and magnitude to which miRNAs impact virus infection is still largely unknown. Here, we used a randomly selected panel of miRNA mutant

Indexed as

Drosophila melanogasterMicroRNAsAnimalsDicistroviridaeGene Expression RegulationHost-Pathogen InteractionsMutationNodaviridaeRNA, ViralSindbis VirusVirus ReplicationMicroRNAsRNA, ViralDrosophila C virusDrosophila melanogasterFlock House virusfunctional screenhost-virus interactionsmicroRNAsSindbis virusvirus infection

Identifiers

PMID42390269
PMCPMC13386962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.