Evidence map›Paper›PMID 42390232›Full record

ArticlemSphere2026

Tools for genetic manipulation of the endemic fungal pathogen

Lucian Duvenage, Alisha Chetty, Darren D Thomson, Elizabeth R Ballou, Nelesh P Govender, Chad A Rappleye, J Claire Hoving

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Lucian DuvenageCMM AFRICA Medical Mycology Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-8173-4644
Alisha ChettyCMM AFRICA Medical Mycology Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-6834-5764
Darren D ThomsonMRC Centre for Medical Mycology, The University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-4800-7717
Elizabeth R BallouMRC Centre for Medical Mycology, The University of Exeter, Exeter, United Kingdom.ORCID 0000-0001-8051-2302
Nelesh P GovenderWits Mycology Division, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Parktown, Gauteng, South Africa.ORCID 0000-0001-7869-9462
Chad A Rappleye *Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0001-7880-5958
J Claire Hoving *CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-7162-5855

Funding

Intracellular Proliferation of the fungal pathogen Histoplasma capsulatumR01AI148561 · NIAID · OHIO STATE UNIVERSITY · PI Chad A Rappleye · 2020 to 2026
$2.5M
NIAID NIH HHS R01 AI148561NIH HHS AI148561Wellcome TrustWellcome Trust 209293/Z/17/ZWellcome Trust 310933/Z/24/Z
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

AscomycotaGenes, ReporterMycosesAnimalsCRISPR-Cas SystemsDisease Models, AnimalGreen Fluorescent ProteinsMacrophagesMicePlasmidsGreen Fluorescent Proteinsanimal modelsEmergomyces africanusmolecular methodsmycology

Identifiers

PMID42390232
PMCPMC13410962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.