Evidence map›Paper›PMID 42390224›Full record

ArticlemSystems2026

Mucin-induced metabolic reprogramming in

Mohammad Mazharul Islam, Glynis L Kolling, Joanna B Goldberg, Katharina Ribbeck, Jason A Papin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Mazharul IslamDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-9745-0344
Glynis L KollingDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-8871-8129
Joanna B GoldbergDepartment of Pediatrics, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-5285-5188
Katharina RibbeckDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Jason A PapinDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-2769-5805

Funding

Multi-scale model of microbial phenotype modulation by mucinsR01AI154242 · NIAID · UNIVERSITY OF VIRGINIA · PI FORD, ROSEANNE, PAPIN, JASON · 2020 to 2024
$3.1M
Systems biology approach to elucidate complex metabolic dependencies in the evolution of antibiotic resistanceR01GM147257 · NIGMS · UNIVERSITY OF VIRGINIA · PI Jason Papin · 2023 to 2026
$1.2M
NIAID NIH HHS R01 AI154242NIGMS NIH HHS R01 GM147257NIH HHS AI154242, GM147257
6 · The paper itself

Abstract

Mucins modulate microbial metabolism, which is crucial in many human infections. It is unknown whether the metabolic alterations induced by mucin are universal or unique across varied clinical isolates of bacterial pathogens. We experimentally profiled a representative set of seven clinical

Indexed as

MucinsPseudomonas aeruginosaAnimalsGene Expression ProfilingGene Expression Regulation, BacterialHumansMetabolic Networks and PathwaysMetabolic ReprogrammingPseudomonas InfectionsTranscriptomeMucinsmetabolic reprogrammingmucinPseudomonas aeruginosatranscriptomics

Identifiers

PMID42390224
PMCPMC13387015

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.