Evidence map›Paper›PMID 42390205›Full record

ArticleThe European journal of neuroscience2026

Superficial Ventral Premotor Pathways to Primary Motor Cortex Shape the Temporal Coordination of Precision Graspinnog.

Andrea Casarotto, Elisa Dolfini, Marta Russo, Giacomo Koch, Luciano Fadiga, Alessandro D'Ausilio

Abstract read
In one paragraph

Article in The European journal of neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea CasarottoIIT@UniFe Center for Translational Neurophysiology of Speech and Communication, Istituto Italiano di Tecnologia, Ferrara, Italy.ORCID 0000-0002-2927-2486
Elisa DolfiniDepartment of Neuroscience and Rehabilitation, Section of Physiology, Università di Ferrara, Ferrara, Italy.
Marta RussoInstitute of Cognitive Sciences and Technologies (ISTC), National Research Council (CNR), Rome, Italy.
Giacomo KochIIT@UniFe Center for Translational Neurophysiology of Speech and Communication, Istituto Italiano di Tecnologia, Ferrara, Italy.
Luciano FadigaIIT@UniFe Center for Translational Neurophysiology of Speech and Communication, Istituto Italiano di Tecnologia, Ferrara, Italy.
Alessandro D'AusilioIIT@UniFe Center for Translational Neurophysiology of Speech and Communication, Istituto Italiano di Tecnologia, Ferrara, Italy.

Funding

HORIZON EUROPE Digital, Industry and Space HORIZON-CL4-2022-DIGITALEMERGING-02-101120727Ministero dell'Università e della Ricerca PRIN 2020: 20208RB4N9NextGenerationEU MOTUS: P2022J8AXYNextGenerationEU PRIN 2022: 2022XW3MJX
6 · The paper itself

Abstract

Goal-directed actions, such as picking up, manipulating, or using objects, are so ubiquitous that impairments in these skills can severely impact quality of life. Reaching-grasping behaviors are driven by a frontoparietal network, with the ventral premotor cortex (PMv) and the primary motor cortex (M1) serving as critical frontal nodes. PMv-M1 connectivity can be modulated using cortico-cortical paired associative stimulation (cc-PAS), which involves repeated paired transcranial magnetic stimulation (TMS) of both nodes. Stimulating M1 with an anterior-posterior (AP) current direction selectively enhances corticospinal excitability during isometric precision grip, but not during isometric power grip. However, it is unclear how the plasticity induction in the more superficial PMv-M1 connectivity may influence the preparation and execution of goal-directed, naturalistic reaching-grasping actions. In this study, participants performed reaching-grasping actions toward small or large objects, requiring precision or power grip, before and after applying the PMv-M1 cc-PAS

Indexed as

Hand StrengthMotor CortexPsychomotor PerformanceAdultEvoked Potentials, MotorFemaleHumansMaleNeuronal PlasticityTranscranial Magnetic StimulationYoung Adultcortico‐cortical paired associative stimulation (cc‐PAS)Hebbian‐like plasticityprimary motor cortex (M1)reaching—graspingventral premotor cortex

Identifiers

PMID42390205
PMCPMC13325708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.