Evidence map›Paper›PMID 42389595›Full record

ArticleiScience2026

A flexible behavioral method for measuring human and artificial intelligence alignment using representational similarity analysis.

Mattson Ogg, Ritwik Bose, James Scharf, Christopher R Ratto, Michael Wolmetz

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mattson OggResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.
Ritwik BoseResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.
James ScharfResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.
Christopher R RattoResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.
Michael WolmetzResearch and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As we consider entrusting large language models (LLMs) with key societal and decision-making roles, measuring their alignment with human cognition becomes critical. This requires methods that can assess how these systems represent information and facilitate comparisons with human understanding across diverse tasks. To meet this need, we adapted representational similarity analysis (RSA), using pairwise ratings to help quantify alignment between AIs and humans. Among the models we studied, GPT-5-mini and Claude Sonnet 4.5 showed the strongest alignment with human text ratings. Llama-4 was the best aligned open-source model. However, gaps between LLM and human behavior remain. No model we studied adequately captured the inter-individual variability observed among human participants, and models only moderately aligned with individual human responses. We demonstrate the utility of this approach across multiple modalities (words, sentences, and images), helping further our understanding of how LLMs encode knowledge, and enabling an examination of alignment with human cognition.

Indexed as

applied sciencesartificial intelligencecomputing methodologylinguisticsnatural language processingsocial sciences

Identifiers

PMID42389595
PMCPMC13320333

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.