Evidence map›Paper›PMID 42389576›Full record

ArticleiScience2026

Central and peripheral neuromuscular mechanisms underlying functional recovery heterogeneity in tibial plateau fractures.

Zihao Sun, Gangqiang Du, Chao Liu, Hongzhen Du, Jianxin Sun, Baoju Wang, Bixuan Duan, Binbin Huang, Meng Guo, Lina Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zihao SunDepartment of Special Education and Rehabilitation, Binzhou Medical University, Yantai, Shandong, China.
Gangqiang DuFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Chao LiuDepartment of Sports Training, Tianjin University of Sport, Tianjin, China.
Hongzhen DuDepartment of Special Education and Rehabilitation, Binzhou Medical University, Yantai, Shandong, China.
Jianxin SunDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Baoju WangDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Bixuan DuanDepartment of Special Education and Rehabilitation, Binzhou Medical University, Yantai, Shandong, China.
Binbin HuangDepartment of Special Education and Rehabilitation, Binzhou Medical University, Yantai, Shandong, China.
Meng GuoDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Lina ZhangDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Pei MaDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Li YuDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Wei LiDepartment of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional recovery after tibial plateau fracture surgery shows substantial heterogeneity, with 30-40% of patients developing persistent limitations that extend beyond peripheral muscle deficits and may involve coupled central neural adaptations. We compared 32 patients with higher (Knee Injury and Osteoarthritis Outcome Score-Activities of Daily Living (KOOS-ADL) ≥80) and 32 with lower (KOOS-ADL ≤70) functional outcomes at 12 months post-surgery using synchronized three-dimensional motion capture, functional near-infrared spectroscopy, and surface electromyography during normal, dual-task, and balance-challenged walking. Routine gait revealed sensorimotor cortex hypoactivation and reduced affected-side ankle co-contraction in the lower-function group; dual-task walking exposed a marked affected-side ankle power deficit; and balance-challenged walking unmasked the largest discriminator, a 32.7% versus 7.3% knee coronal plane range-of-motion asymmetry (

Indexed as

Health sciencesMedical specialtyMedicineOrthopedics

Identifiers

PMID42389576
PMCPMC13319370

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.