Evidence map›Paper›PMID 42389477›Full record

ArticleBrain & spine2026

Short-term clinical outcomes in single-stage vs. two-stage corrective surgery after pedicle subtraction osteotomy for degenerative deformities in an elderly cohort.

Claudius Jelgersma, Daria Samoylenko, Anton Früh, Kiarash Ferdowssian, Robert Mertens, Christian Entenmann, Ahmad Almahozi, Dimitri Tkatschenko, Tarik Alp Sargut, Nils Hecht and 2 more

Abstract read
In one paragraph

Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Claudius JelgersmaDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Daria SamoylenkoDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Anton FrühDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Kiarash FerdowssianDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Robert MertensDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Christian EntenmannDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Ahmad AlmahoziDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Dimitri TkatschenkoDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Tarik Alp SargutDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Nils HechtDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Peter VajkoczyDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.
Lars WesselsDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Corrective spinal surgery involving pedicle subtraction osteotomy is a demanding procedure associated with a high risk of complications, particularly in elderly patients. Staged approaches have been proposed to reduce perioperative risk and patients' burden; nevertheless, evidence in this population is limited. Research question: This study compares single versus two-staged approaches in elderly patients, assessing short-term outcomes and complication severity. Methods: Fifty-one patients who underwent corrective spinal fusion with pedicle subtraction osteotomy between 2014 and 2023 were retrospectively analyzed. Clinical characteristics and complications were compared, with complications classified using the modified Clavien-Dindo-Sink classification. Results: The median age was 70 and 71 years in the single-stage group (1-SG, n = 30) vs. the two-stage group (2-SG, n = 21). Baseline characteristics and the number of instrumented segments (1-SG: 9.7 ± 4.2; 2-SG: 10.6 ± 3.4) were comparable. Cumulative operative time was significantly shorter in 1-SG (431 ± 131 min) compared with 2-SG (653 ± 142 min). However, perioperative parameters, including estimated blood loss, transfusion rate, hospital stay, and discharge modality, showed no significant differences. The incidence and severity of complications within 90 days were also comparable across both groups. Conclusions: This study demonstrates no beneficial effect of staged surgery for corrective spine surgery in elderly patients. The findings suggest that overall surgical invasiveness, rather than timing strategy, is more critical when prolonged operating times and high blood loss are expected.

Indexed as

ComplicationsCorrective spine surgeryElderlyPedicle subtraction osteotomySpinal deformityStaged surgery

Identifiers

PMID42389477
PMCPMC13321370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.