Evidence map›Paper›PMID 42389400›Full record

ArticleJournal of cardiovascular echography

Concomitant Dynamic Left Ventricular Outflow Tract Obstruction and Severe Aortic Stenosis a Case Report and a Literature Review.

Tommaso Crovetto, Fabio Vagnarelli, Vito Maurizio Parato, Alessandro Barbarossa

Abstract readCase Reports
In one paragraph

Article in Journal of cardiovascular echography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Forward Dynamics: Modern Insights into Mitral Systolic Anterior Motion.Journal of cardiovascular development and disease · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tommaso CrovettoDepartment of Cardiovascular Sciences, Cardiology and Arrhythmology Clinic, Marche University Hospital, Ancona, Marche, Italy.
Fabio VagnarelliCardiology Division, Lancisi Cardiovascular Center, Marche University Hospital, Ancona, Marche, Italy.
Vito Maurizio ParatoCardiology and Cardiac Rehabilitation Unit, Madonna del Soccorso Hospital - AST/AP, San Benedetto del Tronto, Marche, Italy.
Alessandro BarbarossaDepartment of Cardiovascular Sciences, Cardiology and Arrhythmology Clinic, Marche University Hospital, Ancona, Marche, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 77-year-old woman presenting with a hypertrophic cardiomyopathy phenotype characterized by hemodynamically significant dynamic left ventricular outflow tract obstruction (LVOTO) due to mitral systolic anterior motion (SAM), in association with aortic stenosis (AS). The clinical presentation included an episode of syncope, followed by progressive exertional dyspnea. Initial transthoracic echocardiography revealed marked septal hypertrophy, a calcified aortic valve with elevated transvalvular gradients, and SAM-induced dynamic LVOTO. Sarcomeric hypertrophic cardiomyopathy (HCM) and its phenocopies were subsequently excluded from the study. Transesophageal echocardiography confirmed the coexistence of severe AS and SAM. Given the complexity of the patient's cardiac condition and the presence of a "porcelain aorta," both surgical and transcatheter aortic valve replacement were deemed high risk. We discuss the diagnostic and therapeutic challenges of this "double-threat" scenario - severe aortic stenosis combined with dynamic LVOTO - and review the relevant literature regarding its hemodynamic implications, imaging strategies, and management approaches, including the concept of the "suicide left ventricle".

Indexed as

Dynamic left ventricular outflow tract obstructionleft ventriclesevere aortic stenosissuicide

Identifiers

PMID42389400
PMCPMC13322586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.