Evidence map›Paper›PMID 42389301›Full record

ArticleJournal of craniovertebral junction & spine

An examination of atlanto-occipital curvature in adult Chiari malformation type 1 and control groups.

Mahsa Karamzadeh, Mohamad Motaz Al Samman, Rick Labuda, Rafeeque A Bhadelia, Jonathan A Millard, Paul D Bishop, Philip A Allen, Thomas J Fultz, Scott B Raymond, Jenny P Tsai and 3 more

Abstract read
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In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mahsa KaramzadehDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Mohamad Motaz Al SammanDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Rick LabudaConquer Chiari, Wexford, PA, USA.
Rafeeque A BhadeliaDepartment of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Jonathan A MillardDepartment of Biomedical Sciences, Edward Via College of Osteopathic Medicine, Blacksburg, VA, USA.
Paul D BishopDepartment of Vascular Surgery, Cleveland Clinic, Cleveland, OH, USA.
Philip A AllenDepartment of Psychology, University of Akron, Akron, OH, USA.
Thomas J FultzDepartment of Vascular Surgery, Cleveland Clinic, Cleveland, OH, USA.
Scott B RaymondNeurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Jenny P TsaiNeurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Muhammad Shazam HussainCerebrovascular Center, Cleveland Clinic, OH, USA.
Rouzbeh AminiDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Francis LothDepartment of Bioengineering, Northeastern University, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare computed tomography (CT) scan-based morphometric measures associated with atlanto-occipital joint (AOJ) instability between Chiari malformation type I (CMI) patients and controls and to examine associations between these measures, clinical symptoms, and established craniocervical/posterior fossa morphometrics in CMI. Materials and Methods: Four AOJ-related morphometric measures were evaluated on CT: condyle-C1 interval (CCI), C1 socket depth-to-length ratio (DL ratio), condyle depth-to-depth ratio (CD ratio), and atlas tilt angle. Measurements were compared between CMI ( Results: Mean CCI was slightly larger in CMI than in controls (1.00 vs. 0.91 mm, Conclusion: Among the AOJ measures examined, only CCI demonstrated a small but statistically significant group difference and a modest association with hypermobility in CMI. The shape of the AOJ curvature was not different between CMI and control. However, further investigation of AOJ-related morphometrics as potential contributors to symptom heterogeneity among CMI patients is necessary.

Indexed as

Atlanto-occipital jointcervicomedullary morphometricsChiari malformationcomputed tomographyposterior fossa decompression surgerysyringomyelia

Identifiers

PMID42389301
PMCPMC13322720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.