Cefepime resistance with preserved ceftriaxone susceptibility in

Amorce Lima, Mackenzie Collins, Mario Jaramillo, Shekina Gonzalez-Ferrer, Anita Sircar, Paul R Allyn, Shangxin Yang

Abstract readCase Reports

In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amorce LimaDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Mackenzie CollinsDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Mario JaramilloDivision of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Shekina Gonzalez-FerrerDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Anita SircarDivision of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Paul R AllynDivision of Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Shangxin YangDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Retrospective case series to describe an unusual cefepime-resistant, ceftriaxone-susceptible phenotype in Patients: Two adult patients with diabetes mellitus and chronic osteomyelitis, one with diabetic foot ulcer and one with infected hip prosthesis, both with prolonged antibiotic treatment. Methods: Clinical data and antimicrobial susceptibility results were reviewed. Whole-genome sequencing was performed using short-read and long-read platforms with hybrid assembly. Resistance gene identification, phylogenetic analysis, and gene copy number estimation were conducted. Results: Three isolates of Conclusions: This study showed that duplication of a transposon-associated

Indexed as

Cefepime resistanceGene duplicationOsteomyelitisOXA-1Proteus mirabilis

Identifiers

PMID42389002

DOI10.1016/j.idcr.2026.e02654

PMCPMC13318549

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