Evidence map›Paper›PMID 42388691›Full record

ArticleGastroenterology & hepatology2026

Beyond Medication: Integrative and Nutrition Therapies for Disorders of Gut-Brain Interaction.

Elyse R Thakur, Kate Scarlata, Brennan Spiegel, David J Hass

Abstract read
In one paragraph

Article in Gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elyse R ThakurWake Forest University School of Medicine and Atrium Health, Charlotte, North Carolina.
Kate ScarlataFor a Digestive Peace of Mind, LLC, Medway, Massachusetts.
Brennan SpiegelCedars-Sinai School of Medicine, Los Angeles, California.
David J HassYale University School of Medicine, New Haven, Connecticut.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disorders of gut-brain interaction (DGBIs), such as irritable bowel syndrome and functional dyspepsia, affect a substantial portion of the global population. These disorders are best conceptualized through a biopsychosocial framework, reflecting the complex interplay and bidirectional communication among biological, psychological, and social factors. While conventional pharmaceutical treatments remain limited in efficacy and patient satisfaction, interest in integrative approaches to care continues to grow. However, despite the increasing use of integrative interventions for DGBIs, their therapeutic targets and underlying mechanisms remain poorly defined. This article aims to describe current and emerging integrative and nutrition-based interventions for DGBIs and evaluate their potential to complement conventional medicine by addressing a broader spectrum of biopsychosocial risk factors.

Indexed as

biopsychosocial factorsDisorders of gut-brain interactionfunctional dyspepsiaintegrative medicineirritable bowel syndromemind-body therapies

Identifiers

PMID42388691
PMCPMC13322314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.