Evidence map›Paper›PMID 42388627›Full record

ReviewFrontiers in oncology2026

Impact of health system interventions to improve access to external beam radiotherapy: a scoping review.

David Chen, Karren Xiao, Russell Leong, Kristen Arnold, Angela Doyle, Fabio Ynoe de Moraes, Paris-Ann Ingledew, Srinivas Raman

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David ChenPrincess Margaret Hospital Cancer Center, Radiation Medicine Program, Toronto, ON, Canada.
Karren Xiao *Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Russell Leong *Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Kristen Arnold *Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Angela DoyleBC Cancer Library, Vancouver, BC, Canada.
Fabio Ynoe de MoraesDivision of Radiation Oncology, Department of Oncology, Kingston General Hospital, Queen's University, Kingston, ON, Canada.
Paris-Ann IngledewDepartment of Radiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.
Srinivas RamanDepartment of Radiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Access to external beam radiotherapy (EBRT) remains heterogeneous across global health systems, particularly in low- and middle-income countries (LMIC). This scoping review aimed to synthesize evidence on health-system interventions intended to improve EBRT access, characterize their outcomes, and identify promising strategies for sustainable and equitable radiotherapy delivery. Methods: A systematic search of Ovid MEDLINE, Embase, and CINAHL from inception to June 30, 2025, identified studies evaluating system-level interventions to improve EBRT access. Eligible interventions included infrastructure expansion, workforce development, operational redesign, telemedicine, financing, and quality improvement initiatives. Data were extracted in duplicate and narratively synthesized by intervention domain. Results: Across 31 included studies, the most frequent intervention domains were infrastructure expansion (45%), workforce development (35%), operational redesign (29%), telemedicine (26%), referral and navigation (19%), and financial reforms (10%). The majority of studies reported improved radiotherapy utilization, reduced waiting times, and higher treatment completion rates. Multi-component programs that integrate interventions such as infrastructure and workforce expansion, operational redesign, tele-radiotherapy, decentralization through hub-and-spoke models, and protocolization of hypofractionation regimens, workforce, and operational redesign, can be a sustainable strategy to progress towards equitable, system-level programs to improve EBRT access. Conclusion: Health-system interventions can meaningfully expand access to EBRT when they align investments in infrastructure, workforce, and operations. Multi-component, equity-focused strategies hold promise for scalable, high-quality radiotherapy delivery to address access disparities. Future research should adopt standardized access metrics and report equity-stratified outcomes to guide national strategies for sustainable scale-up of EBRT.

Indexed as

accessibilityEBRTequityexternal beam radiation therapy (EBRT)health system interventionsustainability

Identifiers

PMID42388627
PMCPMC13318796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.