Evidence map›Paper›PMID 42388585›Full record

ArticleCancer diagnosis & prognosis

The Clinical Impact of Prognostic Nutritional Index at Recurrence of Pancreatic Cancer.

Teruhisa Sakamoto, Kentaro Uehira, Jun Yoshida, Mikiya Kishino, Masaki Morimoto, Yuki Murakami, Kozo Miyatani, Yuji Shishido, Kyoichi Kihara, Tomoyuki Matsunaga and 2 more

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Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Teruhisa SakamotoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Kentaro UehiraDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Jun YoshidaDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Mikiya KishinoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Masaki MorimotoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Yuki MurakamiDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Kozo MiyataniDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Yuji ShishidoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Kyoichi KiharaDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Tomoyuki MatsunagaDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Manabu YamamotoDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
Yoshiyuki FujiwaraDivision of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aim: Most patients with pancreatic cancer experience recurrence after curative surgical resection. Nutritional-related indicators have been evaluated to analyze prognosis in pancreatic cancer. However, it is unknown whether the cachexia index (CXI) or the prognostic nutritional index (PNI) is better for prediction of survival in patients with recurrence of pancreatic cancer. In this study, we compared the ability of the PNI to predict survival at 1 year after recurrence of pancreatic cancer with that of the CXI. Patients and Methods: The study included 113 patients whom we retrospectively identified to have developed recurrence of pancreatic cancer as of September 2025 following pancreatectomy at our Institution between July 2005 and December 2022. Results: The 5-year post-recurrence overall survival rate was 5.8% and the median survival time was 378 days. The 1-year survival curve was significantly better for the high PNI group than the low PNI group and for the high CXI group than the low CXI group ( Conclusion: Patients with a low PNI at the time of recurrence of pancreatic cancer have poorer prognostic outcomes than those with a high PNI. Improvement of nutritional status after curative surgery might improve prognosis after recurrence of pancreatic cancer.

Indexed as

CXIPNIrecurrent pancreatic cancer

Identifiers

PMID42388585
PMCPMC13322098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.