ArticleCase reports in infectious diseases2026
The Diagnosis of Human Neurological Infection Caused by Rabies Virus Using Metagenomic Next-Generation Sequencing: Two Case Reports.
Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- The Diagnosis of Human Neurological Infection Caused by Rabies Virus Using Metagenomic Next-Generation Sequencing: Two Case Reports.Case reports in infectious diseases · 2026Article
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4 authors.
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Abstract
The rabies virus (RABV) causes acute progressive and fatal encephalomyelitis. Two case studies of RABV neurological infection identified using metagenomic next-generation sequencing (mNGS) are presented in this paper. A total of 39 RABV sequences were detected using mNGS in the cerebrospinal fluid (CSF) in Case 1. The detected sequences were located in the 0%-35% range of the enriched and amplified region and had a 27 × sequencing depth. A total of 75 RABV sequences were detected using mNGS in the CSF in Case 2. These cases illustrate that mNGS use during the early diagnosis of infectious diseases is critical. They also indicate that RABV can remain latent in the human body for many years. Disease prevention education for people who have experienced bites or scratches by rabid animals is therefore crucial.
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