Evidence map›Paper›PMID 42388374›Full record

ArticleMaterials today. Bio2026

A DMAHDM-herbal hybrid gargle for orthodontic-associated complications via oral microbiota regulation, inflammation inhibition, and enamel protection.

Yuqing Zhang, Bo Wang, Ce Bian, Chaoran Yu, Mengyao Zhu, Yiman Guo, Honglei Yue, Wenting Yu, Yuxing Bai, Ning Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuqing ZhangDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Bo WangDepartment of Stomatology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Dalian, Liaoning, 116000, PR China.
Ce BianDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Chaoran YuDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Mengyao ZhuDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Yiman GuoDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Honglei YueBeijing Institute of Dental Research, Beijing Stomatological Hospital, Capital Medical University, No. 9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Wenting YuDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Yuxing BaiDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.
Ning ZhangDepartment of Orthodontics, Beijing Stomatological Hospital and School of Stomatology, Capital Medical University, No.9 Fanjiacun Road, Fengtai District, Beijing, 100070, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthodontic appliances are indispensable for achieving therapeutic efficacy, but their complex and irregular architecture compromises oral hygiene, increasing susceptibility to dental caries and periodontal diseases. Conventional gargles primarily target antibacterial effects; however, their prolonged use may disrupt the balance of the oral microbiota, and remains insufficient for controlling periodontal inflammation and preventing enamel demineralization. Herein, a bioactive hybrid gargle integrating

Indexed as

AntibacterialAnti-inflammatoryEnamel demineralizationMicrobiome regulationOrthodontic treatment

Identifiers

PMID42388374
PMCPMC13320463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.