ArticleFrontiers in microbiology2026
Phenotypic and genomic characterization of vB_SauP-INT105, an exopolysaccharide depolymerase-encoding lytic short-tailed phage with antibiofilm activity against
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Methods and results: Plaque morphology revealed a distinctive three-zone halo pattern suggestive of phage-encoded exopolysaccharide depolymerase activity, confirmed by bioinformatic prediction of two candidate depolymerase-encoding ORFs. Electron microscopy showed a bacteriophage with an icosahedral head and a short non-contractile tail. The phage exhibited lytic activity against 86.5% of 37 dairy-associated Conclusion: These results establish INT105 as a genomically safe, environmentally robust and functionally effective phage with strong potential for biocontrol applications in dairy-production environments and broader food-safety and clinical contexts.
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