Evidence map›Paper›PMID 42388270›Full record

ReviewJournal of bone oncology2026

Postoperative survival in patients undergoing surgery for long bone metastases: a systematic review and Meta-analysis of outcomes across primary tumor types.

Tom M de Groot, Jeroen D R Koning, Michelle R Shimizu, Date van der Meij, Olivier Q Groot, Joris J W Ploegmakers, Job N Doornberg, Paul C Jutte

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tom M de GrootDepartment of Orthopaedic Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Jeroen D R KoningDepartment of Orthopaedic Surgery, Amsterdam Medical Centers, Amsterdam, the Netherlands.
Michelle R ShimizuDepartment of Orthopaedic Surgery, Cleveland Clinic Medical Center, Cleveland, OH, USA.
Date van der MeijDepartment of Orthopaedic Surgery, Frisius Medical Center, Leeuwarden, the Netherlands.
Olivier Q GrootDepartment of Orthopaedic Trauma Surgery, Flinders University, Flinders Medical Center, Adelaide, Australia.
Joris J W PloegmakersDepartment of Orthopaedic Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Job N DoornbergDepartment of Orthopaedic Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Paul C JutteDepartment of Orthopaedic Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgery for long bone metastases is performed to alleviate pain, restore function, and improve quality of life. Accurate postoperative survival estimates are essential for surgical planning and shared decision-making, yet no comprehensive synthesis exists across primary tumor types. This systematic review aimed to characterize postoperative survival and its temporal trend in patients undergoing surgery for long bone metastases. Methods: A systematic literature search was performed in PubMed, EMBASE, and Cochrane Library. Studies reporting survival following surgery for long bone metastases were eligible. Pooled survival estimates were computed using restricted maximum likelihood random-effects meta-analysis. Secular trend analysis used weighted linear regression with study sample size as weights. Risk of bias was assessed at the study level using the Joanna Briggs Institute (JBI) critical appraisal tools, with separate checklists applied for cohort studies and case series. Results: A total of 155 studies comprising 27,133 patients were included (1973-2024). Pooled 1-year survival was 47.9% (95% CI 44.1-51.7%, 95% prediction interval 17.7-79.7%, I Conclusions: Postoperative survival varies considerably by primary tumor type and has improved significantly over the past decade. These findings, although non-definitive and descriptive, provide contemporary long-bone metastatic disease specific survival benchmarks to inform prognostic counselling.

Indexed as

Bone metastasesLong bonemeta-analysisPrognosisSurgerySurvivalSystematic review

Identifiers

PMID42388270
PMCPMC13320406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.