Evidence map›Paper›PMID 42388228›Full record

ReviewAsia-Pacific journal of oncology nursing2026

Trimodal prehabilitation for hematopoietic stem cell transplantation: A best evidence summary.

Danni Wu, Limei Xue, Lingzhi Xu, Jie Pan, Tao Chen, Yan Wang, Sufang Zhao

Abstract readReview
In one paragraph

Review in Asia-Pacific journal of oncology nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danni WuDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Limei XueDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Lingzhi XuDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jie PanDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Tao ChenDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yan WangDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Sufang ZhaoDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate and synthesize the best practice evidence of trimodal prehabilitation comprising exercise, nutritional optimization, and psychological support in patients undergoing hematopoietic stem cell transplantation, so as to enhance patients' physiological reserve and stress resistance, and provide a scientific basis and practical reference for formulating individualized prehabilitation programs in clinical practice. Methods: A comprehensive computerized literature search was conducted across multiple databases and evidence sources, including UpToDate, BMJ Best Practice, Guidelines International Network, National Institute for Health and Care Excellence, Scottish Intercollegiate Guidelines Network, National Guideline Clearinghouse, Registered Nurses Association of Ontario, Joanna Briggs Institute, World Health Organization, Cochrane Library, Web of Science, PubMed, CINAHL, China National Knowledge Infrastructure, Wanfang Data, and SinoMed. The search timeframe encompassed literature from September 2015 to September 2025. Results: A total of 11 publications were included, comprising 1 clinical guideline, 2 expert consensus documents, 1 evidence summary, 3 systematic reviews, and 4 randomized controlled trials. The evidence was synthesized across five domains: multidisciplinary team building, exercise prescription, nutritional optimization, psychological support, and precautionary considerations, resulting in the formulation of 34 distinct evidentiary statements. Conclusions: This study synthesizes the best available evidence on trimodal prehabilitation for patients undergoing hematopoietic stem cell transplantation, providing an evidence-based foundation for standardizing pre-transplant rehabilitation management. It is recommended that healthcare professionals, when implementing these recommendations, comprehensively consider the specific clinical context to selectively apply the most appropriate evidence, with the aim of improving patient transplant outcomes. Systematic review registration: This study was registered at the Fudan University Center for Evidence-Based Nursing (Registration No. ES20259181).

Indexed as

Evidence-based summaryHematological malignanciesHematopoietic stem cell transplantationPrehabilitation

Identifiers

PMID42388228
PMCPMC13320315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.