Evidence map›Paper›PMID 42387889›Full record

ReviewJournal of rehabilitation medicine2026

Identification of spastic muscles involved in abnormal joint posture in patients with upper motor neuron syndrome: a narrative review.

Francois Genêt, Vincent Carpentier, Guillaume Chambinaud, Alberto Esquenazzi, Marjorie Salga

Abstract readReview
In one paragraph

Review in Journal of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francois GenêtUPOH (Unité Péri Opératoire du Handicap, Perioperative Disability Unit), Department of PMR « Suivi au long cours », Raymond-Poincaré Hospital, GHU Paris-Saclay, Assistance Publique - Hôpitaux de Paris (AP-HP), Garches, France; Versailles Saint-Quentin-en-Yvelines University (UVSQ - Paris Saclay University), UR 20262 Handistart, UFR Simone Veil Santé, Montigny le Bretonneux, France. francois.genet@aphp.fr.
Vincent CarpentierVersailles Saint-Quentin-en-Yvelines University (UVSQ - Paris Saclay University), UR 20262 Handistart, UFR Simone Veil Santé, Montigny le Bretonneux, France; Department of Physical Medicine and Rehabilitation, Meulan - Les Mureaux Hospital, GHT Yvelines Nord, Les Mureaux, France.
Guillaume ChambinaudUPOH (Unité Péri Opératoire du Handicap, Perioperative Disability Unit), Department of PMR « Suivi au long cours », Raymond-Poincaré Hospital, GHU Paris-Saclay, Assistance Publique - Hôpitaux de Paris (AP-HP), Garches, France; Versailles Saint-Quentin-en-Yvelines University (UVSQ - Paris Saclay University), UR 20262 Handistart, UFR Simone Veil Santé, Montigny le Bretonneux, France.
Alberto EsquenazziJefferson Moss-Magee Rehabilitation, Elkins Park, PA, USA.
Marjorie SalgaUPOH (Unité Péri Opératoire du Handicap, Perioperative Disability Unit), Department of PMR « Suivi au long cours », Raymond-Poincaré Hospital, GHU Paris-Saclay, Assistance Publique - Hôpitaux de Paris (AP-HP), Garches, France; Versailles Saint-Quentin-en-Yvelines University (UVSQ - Paris Saclay University), UR 20262 Handistart, UFR Simone Veil Santé, Montigny le Bretonneux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies have specifically investigated which muscles are involved in abnormal joint posture (AJP) due to muscle spasticity and should therefore be targeted for botulinum toxin injections. This gap has significant implications for treatment efficiency, safety, health economics, and sustainable healthcare. A 2000 to 2025 (July) PubMed search identified 3,488 articles, but only 7 articles met the criteria for providing a method to determine the muscles involved in AJP due to muscle spasticity. Of these, just 2 have proposed how to measure each muscle contribution and only 1 focused on identifying the muscle actually responsible for the observed AJP. There are many strategies for determining the muscles involved in spasticity-related AJP, but they are primarily based on inference. They draw on clinical skills, which incorporate descriptive and functional anatomy, knowledge of different muscle and joint structures, simple rules of biomechanics, determination of the exact phase of the movement involved, consideration of compensatory AJP in these motor control deficient patterns, and, of course, the patient's goals. Achieving the authors' proposed objective would enable the standardization of clinical practices, confirm the effectiveness of treatments for spasticity, particularly botulinum toxin, and ensure that the correct dose is injected in the right muscle.

Indexed as

JointsMotor Neuron DiseaseMuscle, SkeletalMuscle SpasticityPostureBotulinum ToxinsBotulinum Toxins, Type AHumansNeuromuscular AgentsBotulinum ToxinsBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID42387889
PMCPMC13334833

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.