Evidence map›Paper›PMID 42387589›Full record

ArticleTrials2026

Cheek acupuncture for enhancing postoperative recovery after endoscopic sinus surgery: study protocol for a pilot randomized controlled trial.

Meng Wang, Guiyu Lei, Jun Yan, Guyan Wang

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng WangDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Guiyu LeiDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Jun YanDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Guyan WangDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. guyanwang2006@163.com.ORCID http://orcid.org/0000-0001-6957-6356

Funding

Capital's Funds for Health Improvement and Research CFH2024-2-2058
6 · The paper itself

Abstract

backgroundPostoperative pain and sleep disturbance are common after endoscopic sinus surgery (ESS) and may delay postoperative recovery. Acupuncture has demonstrated analgesic and sleep-enhancing effects in perioperative care; however, the impact of cheek acupuncture-a minimally invasive facial microsystem technique-on postoperative recovery after ESS has not been evaluated in randomized controlled trials.

methodsThis single-center, prospective, randomized controlled pilot trial will enroll 90 adults undergoing ESS. Participants will be randomized 1:1 to receive cheek acupuncture or sham cheek acupuncture within 30 min before anesthesia induction. The primary outcome is the Quality of Recovery-15 (QoR-15) score at 24 h postoperatively. Secondary outcomes include the Insomnia Severity Index (ISI), Numerical Rating Scale (NRS) for pain, intraoperative hemodynamics, postoperative care unit (PACU) stay duration, postoperative nausea and vomiting (PONV), and inflammatory biomarkers (serum interleukin-6 [IL-6] and C-reactive protein [CRP]). DISCUSSION: This trial will assess the feasibility, safety, and preliminary efficacy of cheek acupuncture in improving postoperative recovery after ESS. Results will inform the design of a future multicenter randomized trial.

trial registrationChinese Clinical Trial Registry (ChiCTR2500110625). Registered on 16 October 2025.

Indexed as

Acupuncture TherapyCheekEndoscopyParanasal SinusesPostoperative PainAdultChinaFemaleHumansMaleMiddle AgedPain MeasurementPilot ProjectsPostoperative Nausea and VomitingProspective StudiesRandomized Controlled Trials as TopicCheek acupuncture therapy (CAT)Endoscopic sinus surgeryPerioperative carePostoperative recoveryRandomized controlled trial

Identifiers

PMID42387589
PMCPMC13595525

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.