Evidence map›Paper›PMID 42387479›Full record

ArticleBMC veterinary research2026

Impact of Opuntia spp. by-product silage on sheep metabolic profile, rumen fermentation and microbial communities.

A Vastolo, M Tolone, R Gannuscio, A Staropoli, D Giosa, A Bonomo, F Vinale, M I Cutrignelli, M Todaro

Abstract read
In one paragraph

Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A VastoloDepartment of Veterinary Medicine and Animal Production (DMVPA), Università degli Studi di Napoli Federico II, Naples, 80100, Italy.
M ToloneDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, Università degli Studi di Messina, Messina, 98166, Italy.
R GannuscioDepartment of Agricultural, Food and Forest Science (SAAF), Università degli Studi di Palermo, Palermo, 90128, Italy. riccardo.gannuscio@unipa.it.
A StaropoliDepartment of Veterinary Medicine and Animal Production (DMVPA), Università degli Studi di Napoli Federico II, Naples, 80100, Italy.
D GiosaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, Università degli Studi di Messina, Messina, 98166, Italy. domenico.giosa@unime.it.
A BonomoDepartment of Mathematics, Università degli Studi di Pavia, Pavia, 27100, Italy.
F VinaleDepartment of Veterinary Medicine and Animal Production (DMVPA), Università degli Studi di Napoli Federico II, Naples, 80100, Italy.
M I CutrignelliDepartment of Veterinary Medicine and Animal Production (DMVPA), Università degli Studi di Napoli Federico II, Naples, 80100, Italy.
M TodaroDepartment of Agricultural, Food and Forest Science (SAAF), Università degli Studi di Palermo, Palermo, 90128, Italy.

Funding

National Recovery and Resilience Plan (PNNR) of Italy: project Biometric-Call PNNR a cascata-Università della TUSCIA cod. U-Gov PRJ-1776; CUP: J83C22000830005
6 · The paper itself

Abstract

backgroundPrickly pear (Opuntia ficus-indica) by-products represent a promising alternative feed resource for improving the sustainability of sheep production systems in Mediterranean areas. This study evaluated the effects of prickly pear by-product (PPB) silages on rumen fermentation, metabolic profile, and rumen microbiome in lactating ewes. Twelve Valle del Belice ewes were assigned to three dietary treatments (control, CTR; prickly pear peel silage, PPP; and pastazzo silage, PPS) in a Latin square design. Blood biochemical parameters, rumen volatile fatty acids (VFA), and metagenomic profiles were analysed.

resultsPPB inclusion did not induce significant changes in blood biochemical parameters, which remained within physiological ranges. Rumen fermentation parameters were significantly affected, with the PPP diet increasing total VFA concentration and promoting a more glucogenic profile through higher propionate production. The rumen microbiome was dominated by Prevotella, which showed higher relative abundance in the CTR diet. PPB supplementation was associated with shifts in microbial functional profiles, including pathways related to polyphenol degradation, vitamin K2 biosynthesis, and central carbon metabolism, partially consistent with observed changes in rumen fermentation. No significant effects were observed on methanogenesis-related pathways.

conclusionsPrickly pear by-product silages, particularly prickly pear peel, modulate rumen fermentation and microbial functional profiles in lactating ewes without adversely affecting systemic metabolic status.

Indexed as

Gastrointestinal MicrobiomeOpuntiaRumenSilageAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietFatty Acids, VolatileFemaleFermentationMetabolomeSheepFatty Acids, VolatileDairy sheepprickly pear by-productsRumen bacteriaRumen VFASerum biochemical parameters

Identifiers

PMID42387479
PMCPMC13617905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.