Evidence map›Paper›PMID 42387456›Full record

ReviewBMC surgery2026

Reconstruction of the Achilles tendon using LARS artificial ligament in bilateral xanthoma: a case report and literature review.

Cheng Wang, Jiazheng Wang, Chenglin Wu, Jian Zou, Zhongmin Shi

Abstract readCase ReportsReview
In one paragraph

Review in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cheng Wang *National Center for Orthopaedics, Shanghai Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai, 200233, China.
Jiazheng Wang *National Center for Orthopaedics, Shanghai Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai, 200233, China.
Chenglin WuNational Center for Orthopaedics, Shanghai Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai, 200233, China.
Jian Zou *National Center for Orthopaedics, Shanghai Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai, 200233, China. sephirothzou@163.com.
Zhongmin Shi *National Center for Orthopaedics, Shanghai Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai, 200233, China. szm1972@sjtu.edu.cn.

Funding

Science and Technology Commission of Shanghai Municipality 24Y32800100Shanghai Municipal Commission of Economy and Informatization 23SHS03600
6 · The paper itself

Abstract

backgroundAchilles tendon xanthoma (ATX) is a rare benign lesion characterized by lipid deposition within the tendon and is often associated with hyperlipidemia and genetic diseases. Surgery is challenging due to the risk of recurrence and its impact on patients' quality of life. Reconstruction using a synthetic ligament has not been previously reported for this condition. CASE PRESENTATION: A 35-year-old female patient presented with a progressive mass in both heels over 4 years, accompanied by limited ankle dorsiflexion (5°-10°), a Visual Analogue Scale (VAS) score of 6, and an American Orthopaedic Foot and Ankle Society (AOFAS) score of 51. Laboratory evaluation after 6 months of atorvastatin therapy (20 mg/day) revealed persistent hypertriglyceridemia (3.45 mmol/L) and borderline hypercholesterolemia (total cholesterol 5.77 mmol/L, low-density lipoprotein 3.93 mmol/L). Magnetic resonance imaging showed diffuse thickening of both Achilles tendons. After thorough discussion and informed consent, the patient underwent total xanthoma excision combined with Achilles tendon reconstruction using a LARS artificial ligament. At the 2-year follow-up, the patient reported no pain or swelling, achieved a VAS score of 0 and an AOFAS score of 90, and demonstrated full recovery of muscle strength and joint motion without clinical or radiological signs of recurrence or foreign body reaction.

conclusionsTotal excision combined with Achilles tendon reconstruction using a LARS artificial ligament might offer a potential alternative for patients with Achilles tendon xanthoma who have high functional demands, considering its avoidance of donor site morbidity, early postoperative recovery, and sufficient biomechanical strength.

Indexed as

Achilles TendonPlastic Surgery ProceduresXanthomatosisAdultFemaleHumansAchilles tendonArtificial ligamentCase reportSurgeryXanthoma

Identifiers

PMID42387456
PMCPMC13488204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.