Evidence map›Paper›PMID 42387351›Full record

Trial reportBMC pregnancy and childbirth2026

Ulipristal acetate for use in medical management of early pregnancy loss: a pilot feasibility study.

Jill M Hagey, Jennifer H Tang, Jessica E Morse, Amy G Bryant

Registry-linked trialAbstract readClinical Trial, Phase II
In one paragraph

Trial report in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05216952 (Ulipristal Acetate for Use in Early Pregnancy Loss), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05216952 phase2completednot on this map

Ulipristal Acetate for Use in Early Pregnancy Loss: A Phase 2 Pilot Feasibility Study

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2022 to 2023Enrolled3ConditionsMissed Abortion, Anembryonic Pregnancy, Non-Viable PregnancyArmsUlipristal Acetate Tablets, Misoprostol Pill
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jill M HageyDivision of Women's Community and Population Health, Duke Department of Obstetrics and Gynecology, Duke University, DUMC 3084, 236 Baker House 200 Trent Drive, 2301 Erwin Road, Durham, NC, 27710, USA. jmhagey@gmail.com.
Jennifer H TangDivision of Complex Family Planning, Department of Obstetrics and Gynecology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC, 27514, USA.
Jessica E MorseDivision of Complex Family Planning, Department of Obstetrics and Gynecology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC, 27514, USA.
Amy G BryantDivision of Complex Family Planning, Department of Obstetrics and Gynecology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC, 27514, USA.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill UL1TR002489School of Medicine, University of North Carolina at Chapel Hill Center for Maternal and Infant Health Cefalo Bowes Young Researcher AwardSociety of Family Planning Complex Family Planning Fellowship
6 · The paper itself

Abstract

Mifepristone availability for medical management of early pregnancy loss (EPL) is limited in some settings. We report a single site, single arm pilot of ulipristal acetate for EPL management as an alternative to mifepristone. While recruitment was challenging, all participants adhered to study protocol and passed their pregnancy without additional intervention.

trial registrationClinicalTrials.gov (ID NCT05216952), registered January 19, 2022, https//clinicaltrials.gov/study/NCT05216952.

Indexed as

Abortifacient Agents, SteroidalAbortion, SpontaneousNorpregnadienesAdultFeasibility StudiesFemaleHumansMifepristonePilot ProjectsPregnancyPregnancy Trimester, FirstAbortifacient Agents, SteroidalMifepristoneNorpregnadienesulipristal acetateEarly pregnancy lossFeasibilityMedical management of miscarriageMifepristoneMiscarriagePilot studyUlipristal acetate (UPA)

Identifiers

PMID42387351
PMCPMC13595723

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.