Trial reportClinical oral implants research2026
Evaluation of the Adjunctive Use of Er:YAG Laser or Erythritol Air-Polishing in the Non-Surgical Treatment of Peri-Implantitis: A Pilot RCT.
Trial report in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03451981 (Evaluation of the Adjunctive Use of Er), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Adjunctive Use of Er:YAG Laser or Erythritol Air-polishing in the Non-surgical Treatment of Peri-implantitis: a RCT
Who cites it
1 citing paper in PubMed.
- The immune-microbe-metal triad: a vicious cycle driving biomaterial corrosion in the oral inflammatory microenvironment.Bioactive materials · 2027Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimEvaluate the efficacy of adjunctive mechanical/physical decontamination to non-surgical submarginal instrumentation in patients with peri-implantitis. MATERIAL AND
methodsPatients with at least one implant diagnosed with peri-implantitis were included in this 6-month single-masked randomized clinical trial with three parallel groups: non-surgical submarginal instrumentation with titanium curettes (control); control plus erythritol air-polishing (test 1) and control plus Er:YAG laser (test 2). Clinical variables were collected at baseline, 1, 3 and 6 months. The primary outcome was probing pocket depth (PPD) reduction. Secondary outcomes included bleeding on probing (BoP) reduction and endpoint of therapy (implants with PPD ≤ 5 mm, BoP ≤ 1 site, no suppuration). A multilevel logistic model was computed to evaluate the predictive value of implant- and patient-level variables.
resultsForty-seven patients (84 implants) were enrolled. PPD reductions were observed in all groups (mean: 1-1.4 mm at 1 month), remaining stable at 3 months, with slight relapse at 6 months. All treatments led to significant BoP reduction (24%-36%) at 1 month, with no further significant changes at later follow-ups and no intergroup differences. Therapeutic endpoint rates were 12%-18%. Multilevel analysis suggested an association between the presence of ≥ 2 mm vestibular keratinized mucosa and the use of Er:YAG with higher odds of achieving treatment success. Healing was uneventful in all groups, except for one case of surgical emphysema associated with erythritol air-polishing.
conclusionIrrespective of the adjunctive treatment modality, achievement of peri-implantitis therapeutic endpoint was limited across groups. Possible associations with treatment outcomes were observed; these findings require confirmation in larger studies.
trial registrationClinicalTrials.gov identifier: NCT03451981.
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