Evidence map›Paper›PMID 42387257›Full record

ArticleThe Medical journal of Australia2026

Self-Poisoning With Prazosin and Its Off-Label Use in Australia, 2014-2024: Analysis of NSW Poisons Information Centre Data.

Olivia B E Lal, Nicholas A Buckley, Rose Cairns

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Medical journal of Australia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivia B E LalSchool of Medicine, The University of Notre Dame Australia, Darlinghurst, New South Wales, Australia.ORCID https://orcid.org/0009-0005-7133-4280
Nicholas A BuckleyNSW Poisons Information Centre, Children's Hospital at Westmead, Westmead, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6326-4711
Rose CairnsNSW Poisons Information Centre, Children's Hospital at Westmead, Westmead, New South Wales, Australia.ORCID https://orcid.org/0000-0002-8946-5079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NSW Poisons Information Centre data identified 1030 deliberate prazosin self-poisonings over 11 years, rising from 13 to 170 per year (2014-2024). Young women predominated, likely due to expanded off-label (but accepted) psychiatric use of prazosin. Better evidence on benefits of off-label use is needed to justify increasing risks.

Indexed as

Drug OverdoseOff-Label UsePoison Control CentersPrazosinSuicide, AttemptedAdolescentAdultFemaleHumansNew South WalesYoung AdultPrazosinadolescent psychiatryantihypertensive agentsdrug overdoseharm reductionpoison control centrespost‐traumatic stress disorderpsychotropic drugssuicidetherapeutic goods administrationtoxicology

Identifiers

PMID42387257
PMCPMC13323588

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.