ArticleJournal of natural medicines2026
Garcinuntones A‒C, three new polyprenylated xanthones with cytotoxic and anti-HIV-1 activities from Garcinia nuntasaenii.
Article in Journal of natural medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Three previously undescribed polyprenylated xanthone derivatives named garcinuntones A‒C (1 - 3), together with fifteen known compounds (4 - 18) were isolated from the leaves and twigs of Garcinia nuntasaenii Ngerns. & Suddee (Clusiaceae). Their structures were determined by analysis of their physical and spectroscopic data and by comparison with those of related compounds reported in the literature. The absolute configuration of garcinuntone B (2) was established by single crystal X-ray crystallographic analysis using Cu Kα radiation data. Cytotoxic activity against several cancer cell lines (P-388, KB, HT-29, MCF-7, A549, and ASK) and anti-HIV-1 activity using syncytium inhibition and anti-HIV-1 reverse transcriptase assays of some isolated compounds were evaluated. Garcinuntone B exhibited cytotoxicity against some tested cell lines with IC
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