Evidence map›Paper›PMID 42387099›Full record

ArticleJournal of autism and developmental disorders2026

Behavior Regulation Abilities in Children With Prader-Willi Syndrome and Their Impact on Daily Life: At the Crossroads of Cognitive and Emotional Development.

Nawelle Famelart, A M Camblats, J Cortadellas, M Valette, C Brochado, S Faye, C Molinas, M Glattard, J Maire, S Çabal and 3 more

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nawelle FamelartCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France. famelart.n@chu-toulouse.fr.ORCID http://orcid.org/0000-0001-5428-9872
A M CamblatsLabPsy UR 4139, Université de Bordeaux, Bordeaux, France.
J CortadellasCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
M ValetteCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
C BrochadoCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
S FayeCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
C MolinasCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
M GlattardCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
J MaireResearch Unit CERES, Institut Catholique de Toulouse, Toulouse, France.
S ÇabalCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
G DieneCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
M TauberCentre de Référence Maladies Rares PRADORT, Hôpital des Enfants, CHU de Toulouse, 330, Avenue de Grande Bretagne, TSA 70034, 31059, Toulouse Cedex 9, France.
V PostalLabPsy UR 4139, Université de Bordeaux, Bordeaux, France.

Funding

Fondation Maladies Rares Fondation Maladies Rares
6 · The paper itself

Abstract

purposePrader-Willi Syndrome (PWS) is a rare, complex, genetic neurodevelopmental disorder that induces a hypothalamic dysfunction with a global developmental delay and specific trajectories. Behavioral and psychiatric disorders are recurrent in PWS, emerging during childhood and varying considerably in their manifestations. This study aimed to gain a better understanding of the relationship between emotion, cognitive and behavioral regulation abilities in children with PWS, and explore the impact on daily life.

methodsTwenty-five children with PWS aged between 9 and 15 took part in the study, along with an equal number of age-matched control children. A series of assessments was proposed to children and their parents to measure cognitive and executive competencies, affective and behavioral problems, and family impact.

resultsThe children with PWS were clearly distinguished from the control group, displaying marked deficits in cognitive skills, including executive ones, and affective problems. Inter-task correlation analyses showed that many variables were significantly interrelated in the PWS group, in contrast with the control group. Inter-individual variation was strong and cluster analyses revealed that three subgroups emerged; one marked by cognitive and executive deficits, a second by a high level of affective problems, while a third displayed relatively preserved cognitive, executive and emotional skills. The three clusters did not differ in the family impact.

conclusionThe variability of behavioral problems observed in children with PWS seems to be underpinned by cognitive and emotional regulatory mechanisms. This original approach is discussed in light of the literature.

Indexed as

Behavioral regulationChildrenCognitionEmotionImpact of familyPrader-Willi syndrome

Identifiers

PMID42387099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.