Evidence map›Paper›PMID 42386969›Full record

ArticleNature2026

Connecting single-cell transcriptomes to projectomes in the mouse visual cortex.

Staci A Sorensen, Nathan W Gouwens, Yun Wang, Matt Mallory, Agata Budzillo, Rachel Dalley, Brian R Lee, Olga Gliko, Hsien-Chi Kuo, Xiuli Kuang and 108 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

118 authors.

Staci A Sorensen *Allen Institute for Brain Science, Seattle, WA, USA. stacis@alleninstitute.org.ORCID http://orcid.org/0000-0002-6799-2126
Nathan W Gouwens *Allen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8429-4090
Yun Wang *Allen Institute for Brain Science, Seattle, WA, USA.
Matt MalloryAllen Institute for Brain Science, Seattle, WA, USA.
Agata BudzilloAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2723-3272
Rachel DalleyAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7461-7845
Brian R LeeAllen Institute for Brain Science, Seattle, WA, USA.
Olga GlikoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5014-7209
Hsien-Chi KuoAllen Institute for Brain Science, Seattle, WA, USA.
Xiuli KuangSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Rusty MannAllen Institute for Brain Science, Seattle, WA, USA.
Leila AhmadiniaAllen Institute for Brain Science, Seattle, WA, USA.
Lauren AlfilerAllen Institute for Brain Science, Seattle, WA, USA.
Fahimeh BaftizadehAllen Institute for Brain Science, Seattle, WA, USA.
Katherine S BakerAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5454-8026
Sarah BannickAllen Institute for Brain Science, Seattle, WA, USA.
Darren BertagnolliAllen Institute for Brain Science, Seattle, WA, USA.
Kris BickleyAllen Institute for Brain Science, Seattle, WA, USA.
Phil BohnAllen Institute for Brain Science, Seattle, WA, USA.
Jasmine BombenAllen Institute for Brain Science, Seattle, WA, USA.
Chris BowmanAllen Institute for Brain Science, Seattle, WA, USA.
Gabriella BoyerAllen Institute for Brain Science, Seattle, WA, USA.
Krissy BrounerAllen Institute for Brain Science, Seattle, WA, USA.
Dillan BrownAllen Institute for Brain Science, Seattle, WA, USA.
Alex CahoonAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0009-0006-9468-1696
Natalie ChenAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0009-0007-5525-5536
Chao ChenSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Kai ChenSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Maggie ChvilicekAllen Institute for Brain Science, Seattle, WA, USA.
Forrest CollmanAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0280-7022
Tanya L DaigleAllen Institute for Brain Science, Seattle, WA, USA.
Tim DawesAllen Institute for Brain Science, Seattle, WA, USA.
Rebecca de FratesAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7820-093X
Nick DeeAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2831-9254
Maxwell DeParteeAllen Institute for Brain Science, Seattle, WA, USA.
Tom EgdorfAllen Institute for Brain Science, Seattle, WA, USA.
Laila El-HifnawiAllen Institute for Brain Science, Seattle, WA, USA.
Rachel EnstromAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-0100-927X
Luke EspositoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3565-9126
Colin FarrellAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3487-3064
Rohan GalaAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1872-0957
Clare GamlinAllen Institute for Brain Science, Seattle, WA, USA.
Amanda GaryAllen Institute for Brain Science, Seattle, WA, USA.
Andrew GlombAllen Institute for Brain Science, Seattle, WA, USA.
Olena GerasymchukAllen Institute for Brain Science, Seattle, WA, USA.
Jeff GoldyAllen Institute for Brain Science, Seattle, WA, USA.
Hong GuAllen Institute for Brain Science, Seattle, WA, USA.
Kristen HadleyAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4504-8724
Mike HawrylyczAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5741-8024
Alex HenryAllen Institute for Brain Science, Seattle, WA, USA.
Dijon HillAllen Institute for Brain Science, Seattle, WA, USA.
Karla E HirokawaAllen Institute for Brain Science, Seattle, WA, USA.
Zili HuangSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Katelyn JohnsonAllen Institute for Brain Science, Seattle, WA, USA.
Zoe JuneauAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-8860-5260
Sara KebedeAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3775-1583
Lisa KimAllen Institute for Brain Science, Seattle, WA, USA.
Lauren KruseAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3428-2443
Changkyu LeeAllen Institute for Brain Science, Seattle, WA, USA.
Arielle L LeonAllen Institute for Brain Science, Seattle, WA, USA.
Phil LesnarAllen Institute for Brain Science, Seattle, WA, USA.
Quinn LheureuxAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3376-2031
Anan LiBritton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Yaoyao LiSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Elizabeth LiangAllen Institute for Brain Science, Seattle, WA, USA.
Katie LinkAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2387-0116
Michelle MaxwellAllen Institute for Brain Science, Seattle, WA, USA.
Medea McGrawAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-5267-489X
Delissa A McMillenAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3413-4424
Alice MukoraAllen Institute for Brain Science, Seattle, WA, USA.
Lindsay NgAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4134-1608
Thomas OchoaAllen Institute for Brain Science, Seattle, WA, USA.
Aaron OldreAllen Institute for Brain Science, Seattle, WA, USA.
Daniel ParkAllen Institute for Brain Science, Seattle, WA, USA.
Christina Alice PomAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9057-040X
Zoran PopovichDepartment of Computer Science and Engineering, University of Washington, Seattle, WA, USA.
Lydia PotekhinaAllen Institute for Brain Science, Seattle, WA, USA.
Ram RajanbabuAllen Institute for Brain Science, Seattle, WA, USA.
Shea RansfordAllen Institute for Brain Science, Seattle, WA, USA.
Melissa R RedingAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9845-1827
Augustin RuizAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-8361-5152
David SandmanAllen Institute for Brain Science, Seattle, WA, USA.
Martin SchroedterAllen Institute for Brain Science, Seattle, WA, USA.
Josh SevignyAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-9297-4800
Lyudmila ShulgaAllen Institute for Brain Science, Seattle, WA, USA.
La'Akea SivertsAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-1385-086X
Cliff R SlaughterbeckAllen Institute for Brain Science, Seattle, WA, USA.
Kimberly A SmithAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3142-1970
Michelle StoecklinAllen Institute for Brain Science, Seattle, WA, USA.
Josef SulcAllen Institute for Brain Science, Seattle, WA, USA.
Susan M SunkinAllen Institute for Brain Science, Seattle, WA, USA.
Michael TieuAllen Institute for Brain Science, Seattle, WA, USA.
Jonathan T TingAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8266-0392
Jessica TrinhAllen Institute for Brain Science, Seattle, WA, USA.
Ramel VelascoAllen Institute for Brain Science, Seattle, WA, USA.
Sara VargasAllen Institute for Brain Science, Seattle, WA, USA.
Dave VumbacoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8115-3081
Miranda WalkerAllen Institute for Brain Science, Seattle, WA, USA.
Micheal WangAllen Institute for Brain Science, Seattle, WA, USA.
Adrian WannerAriadne.ai, Buchrain, Switzerland.ORCID http://orcid.org/0000-0002-5864-8577
Jack WatersAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2312-4183
Mirah WellsAllen Institute for Brain Science, Seattle, WA, USA.
Grace WilliamsAllen Institute for Brain Science, Seattle, WA, USA.
Julia A WilsonAllen Institute for Brain Science, Seattle, WA, USA.
Wei XiongSchool of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, China.
Ed S LeinAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9012-6552
Jim BergAllen Institute for Brain Science, Seattle, WA, USA.
Brian E KalmbachAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3136-8097
Shenqin YaoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2992-4752
Hui GongBritton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0001-5519-6248
Qingming LuoState Key Laboratory of Digital Medical Engineering, School of Biomedical Engineering, Hainan University, Haikou, China.ORCID http://orcid.org/0000-0002-6725-9311
Quanxin WangAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0007-7935
Lydia NgAllen Institute for Brain Science, Seattle, WA, USA.
Uygar SümbülAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7134-8897
Zizhen YaoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-9361-5607
Tim JarskyAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4399-539X
Bosiljka TasicAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6861-4506
Hongkui ZengAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0326-5878

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7M
BRAIN CONNECTS: PatchLink, scalable tools for integrating connectomes, projectomes, and transcriptomesU01NS132267 · NINDS · ALLEN INSTITUTE · PI JARSKY, TIM M, SORENSEN, STACI A · 2023 to 2025
$5.7M
Scalable tools for consistent identification of neuronal cell types in mouse and humanRF1MH128778 · NIMH · ALLEN INSTITUTE · PI SORENSEN, STACI A, SUMBUL, UYGAR · 2021 to 2021
$1.1M
NIMH NIH HHS RF1 MH128778NIMH NIH HHS U19 MH114830NINDS NIH HHS U01 NS132267
6 · The paper itself

Abstract

The mammalian brain consists of diverse neuron types with various functions. Recent single-cell RNA sequencing approaches have led to a whole-brain taxonomy of transcriptomically defined cell types

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.