Evidence map›Paper›PMID 42386962›Full record

ArticleNature2026

A secreted endosymbiont protein essential for colonizing host cells.

Gerald P Maeda, Allen Z Xue, Ethan W Yu, Aadhunik Sundar, Derrick L Kamp, J Elijah Powell, Thomas E Smith, Nancy A Moran

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Gerald P MaedaDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Allen Z XueDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0009-0000-0002-7180
Ethan W YuDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0009-0003-3243-8269
Aadhunik SundarDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Derrick L KampDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
J Elijah PowellDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0002-2758-6174
Thomas E SmithDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Nancy A MoranDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA. nancy.moran@austin.utexas.edu.ORCID http://orcid.org/0000-0003-2983-9769

Funding

Elucidating the molecular bases of species interactions in host-associated bacterial communitiesR35GM131738 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI MORAN, NANCY A. · 2019 to 2023
$2.0M
The molecular bases of interbacterial and bacterial-host interactions in microbial communitiesR35GM158145 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Nancy A. Moran · 2025 to 2026
$793k
NIGMS NIH HHS R35 GM131738NIGMS NIH HHS R35 GM158145
6 · The paper itself

Abstract

Intracellular bacterial symbioses have arisen myriad times in eukaryotes, with dozens known from insects alone

Indexed as

AphidsBacterial ProteinsBuchneraSymbiosisActinsAnimalsCytoplasmEmbryonic DevelopmentEmbryo, NonmammalianFemaleLysosomesActinsBacterial Proteins

Identifiers

PMID42386962
PMCPMC13468123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.