ArticleExperimental & molecular medicine2026
Exercise-stimulated primary cilia on preosteoclasts promote periosteal-bone formation.
Article in Experimental & molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Exercise profoundly impacts cortical bones that are refractory to current drugs. However, the mechanisms underlying these changes remain unclear. Here we show that mechanosensitive primary cilia on myeloid-lineage preosteoclasts have a critical role in mediating exercise-induced periosteal-bone formation. We crossed Cx3cr1-Cre or Ctsk-Cre mice with Ift88
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