ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Short-term outcomes associated with surfactant use in respiratory distress in late preterm to early term infants.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEvaluate surfactant therapy and clinical outcomes including length of hospital stay (LOS), CPAP, and mechanical ventilation in late preterm to early term infants. STUDY
designA single-center retrospective study of 401 eligible infants 33-38 + 6 weeks. Surfactant administration included INSURE (INtubation-SURfactant-Extubation), LISA (Less Invasive Surfactant Administration), and endotracheal with prolonged invasive ventilation.
results114 (28%) received surfactant. Surfactant-treated infants had longer LOS (16 ± 11 vs 12 ± 9 days, p < 0.001) compared to non-treated. Infants who received INSURE/LISA (n = 43) had shorter LOS (14 ± 9 vs 18 ± 12 days, p = 0.04) than endotracheal surfactant with prolonged mechanical ventilation (n = 71). Infants who received INSURE/LISA had similar LOS to non-surfactant-treated infants (14 ± 9 vs 13 ± 9 days, p = 0.47).
conclusionSurfactant administration was associated with longer hospitalization compared to non-treated infants. INSURE/LISA shortened LOS compared to surfactant with prolonged ventilation. In late preterm and early term infants that require surfactant for RDS, less invasive methods reduce LOS.
Identifiers
42386899What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.