Observational studyScientific reports2026
Lifetime and acute risk of suicidality by profiles of early life adversity: an observational cohort study in a high-risk population.
Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early life adversity in the form of child maltreatment (CM) is a transdiagnostic risk factor for suicidal ideation and behavior (SIB), yet its heterogeneity and relevance for lifetime versus acute SIB and psychotherapy outcomes remain unclear. In an observational cohort of 240 high-risk adults with borderline personality disorder (42.5%) or persistent depressive disorder (57.5%), lifetime and acute SIB were assessed using the Columbia-Suicide Severity Rating Scale. CM profiles were derived using a data-driven clustering approach based on the Childhood Trauma Questionnaire. Associations between CM profiles, SIB, and symptom change during inpatient cognitive behavioral analysis system of psychotherapy (CBASP) or dialectical behavior therapy (DBT) were examined. Seven distinct CM profiles were identified. A profile characterized by physical and emotional abuse and emotional neglect was associated with elevated lifetime risk for active suicidal ideation with plan and intent and for potentially lethal suicide attempts, compared with minimal CM. CM profiles were not associated with acute SIB or their reduction during inpatient psychotherapy, although differential depressive symptom change by CM profile was observed following CBASP but not DBT. These findings suggest that CM profiling may inform lifetime SIB risk assessment and require replication in larger samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.