SynthesisThe Laryngoscope2026
Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review.
Synthesis in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review.The Laryngoscope · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNasal septal perforation (NSP) repair using the anterior ethmoidal artery (AEA) flap is an emerging endoscopic technique. This systematic review aimed to provide a comprehensive overview of the AEA flap technique, its variations, and its efficacy in repairing NSPs. DATA SOURCES: MEDLINE, Embase, CENTRAL, and Web of Science were searched. This study was reported per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines from 1946 to 2026. REVIEW
methodsThe aforementioned search yielded 2838 results. Animal and cadaver studies, editorials, abstracts, and studies that did not address NSP repair with surgical flaps were excluded. After full-text review of 164 studies, 16 were included.
resultsA total of 249 patients were captured (223 adults, 26 pediatric). For adults, 175 patients underwent the original AEA flap technique with (N = 74) or without (N = 101) an interposition graft, such as tragal cartilage, acellular dermal, or porcine collagen grafts. All pediatric and 48 adult patients underwent various modified AEA flap techniques. For the original AEA flap, mean reported NSP size ranged from 12.8 to 22 mm and postoperative follow-up time ranged from 3 to 51 months. Overall, NSP closure success rate was 84.6% (N = 148/175) for the AEA flap. Closure success rate was 83.8% (N = 62/74) for those with an interposition graft and 85.1% (N = 86/101) for patients without a graft (p = 0.81, Cramer's V = 0.02).
conclusionsWith an overall closure success rate of 84.6%, the AEA flap is a reliable endoscopic technique for repairing NSPs < 2.5 cm. Emerging AEA flap modifications may further improve outcomes, while enabling repair of larger perforations. LEVEL OF EVIDENCE: N/A.
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